BDBM3740 US8530670, 27
SMILES: O=C1C=C(C(N1c1ccc2nc[nH]c2c1)c1ccc(cc1)N1CCOCC1)N1CCCCC1
InChI Key: InChIKey=ZGMJMJGEMCIZHE-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutaminyl Cyclase (Homo sapiens (Human)) | BDBM3740 (US8530670, 27) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 4.60 | -11.6 | 46.1 | n/a | n/a | n/a | n/a | n/a | 30 |
Probiodrug AG US Patent | Assay Description This novel assay was used to determine the kinetic parameters for most of the QC substrate. QC activity was analyzed spectrophotometrically using a ... | US Patent US8530670 (2013) BindingDB Entry DOI: 10.7270/Q2PK0DTD | |||||||||||
More data for this Ligand-Target Pair |