BDBM38199 US10093650, Example 7::US10329273, Example 22

SMILES: Fc1cc(OCCCC(F)(F)F)ccc1[C@@]1(CC(c2ccn(n2)C2CC2)=C(C(=O)N1)n1nn[nH]c1=O)C(F)(F)F

InChI Key: InChIKey=IVLUAGYBDRGAPC-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 38199   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM38199 (US10093650, Example 7 | US10329273, Example 22) Show SMILES Fc1cc(OCCCC(F)(F)F)ccc1[C@@]1(CC(c2ccn(n2)C2CC2)=C(C(=O)N1)n1nn[nH]c1=O)C(F)(F)F |r,c:28| Show InChI InChI=1S/C12H17O3P/c1-11(2)9-12(3,13)16(14,15-11)10-7-5-4-6-8-10/h4-8,13H,9H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	173	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				US Patent US10093650 (2018) BindingDB Entry DOI: 10.7270/Q22809MS
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM38199 (US10093650, Example 7 | US10329273, Example 22) Show SMILES Fc1cc(OCCCC(F)(F)F)ccc1[C@@]1(CC(c2ccn(n2)C2CC2)=C(C(=O)N1)n1nn[nH]c1=O)C(F)(F)F |r,c:28| Show InChI InChI=1S/C12H17O3P/c1-11(2)9-12(3,13)16(14,15-11)10-7-5-4-6-8-10/h4-8,13H,9H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Rutgers University					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				ACS Chem Biol 1: 702-12 (2006) BindingDB Entry DOI: 10.7270/Q2MP55KP
					More data for this Ligand-Target Pair
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM38199 (US10093650, Example 7 | US10329273, Example 22) Show SMILES Fc1cc(OCCCC(F)(F)F)ccc1[C@@]1(CC(c2ccn(n2)C2CC2)=C(C(=O)N1)n1nn[nH]c1=O)C(F)(F)F |r,c:28| Show InChI InChI=1S/C12H17O3P/c1-11(2)9-12(3,13)16(14,15-11)10-7-5-4-6-8-10/h4-8,13H,9H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	173	n/a	n/a	n/a	n/a	n/a	n/a
Rutgers University					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				ACS Chem Biol 1: 702-12 (2006) BindingDB Entry DOI: 10.7270/Q2MP55KP
					More data for this Ligand-Target Pair