null
SMILES: CC(O)(COC(=O)c1ccc(cc1)C#N)[C@@H]1C[C@H](OC(=O)c2ccc(cc2)C#N)[C@@]2(C)Oc3cc(oc(=O)c3C(=O)[C@@H]2C1)-c1cccnc1
InChI Key: InChIKey=WEOCJMZXRUXKAV-NSZDKMDOSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sterol O-acyltransferase 2 (Homo sapiens (Human)) | BDBM383178 (US10278962, Compound 13) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University | Assay Description 1. Purpose:The analogues of Pyripyropene A structure were tested for their inhibitory effect on ACAT2 activity at intact cellular level by a method i... | J Med Chem 51: 5594-607 (2008) BindingDB Entry DOI: 10.7270/Q2CF9SF8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Homo sapiens (Human)) | BDBM383178 (US10278962, Compound 13) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University | Assay Description 1. Purpose:The analogues of Pyripyropene A structure were tested for their inhibitory effect on ACAT2 activity at intact cellular level by a method i... | J Med Chem 51: 5594-607 (2008) BindingDB Entry DOI: 10.7270/Q2CF9SF8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM383178 (US10278962, Compound 13) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.78E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Taiwan University | Assay Description 1. Purpose:The analogues of Pyripyropene A structure were tested for their inhibitory effect on ACAT2 activity at intact cellular level by a method i... | J Med Chem 51: 5594-607 (2008) BindingDB Entry DOI: 10.7270/Q2CF9SF8 | |||||||||||
More data for this Ligand-Target Pair |