BDBM3843 1-Phenylbenzimidazole deriv. 60::1-Phenylbenzimidazole-4-carboxamide Hydrochloride::1-phenyl-1H-1,3-benzodiazole-4-carboxamide
SMILES: NC(=O)c1cccc2n(cnc12)-c1ccccc1
InChI Key: InChIKey=WRSQPWFEWNUDQR-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fibroblast growth factor receptor 1 (Homo sapiens (Human)) | BDBM3843 (1-Phenylbenzimidazole deriv. 60 | 1-Phenylbenzimid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Auckland | Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe... | J Med Chem 41: 5457-65 (1998) Article DOI: 10.1021/jm9804681 BindingDB Entry DOI: 10.7270/Q24T6GJC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Platelet-derived growth factor receptor beta (Homo sapiens (Human)) | BDBM3843 (1-Phenylbenzimidazole deriv. 60 | 1-Phenylbenzimid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Auckland | Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe... | J Med Chem 41: 5457-65 (1998) Article DOI: 10.1021/jm9804681 BindingDB Entry DOI: 10.7270/Q24T6GJC | |||||||||||
More data for this Ligand-Target Pair |