BDBM38921 MLS000056851::N-(5-ethylsulfanyl-1,3,4-thiadiazol-2-yl)pyridine-2-carboxamide::N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-2-pyridinecarboxamide::N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]picolinamide::SMR000067448::cid_2121806

SMILES: CCSc1nnc(NC(=O)c2ccccn2)s1

InChI Key: InChIKey=UMDFROBIOXQDLW-UHFFFAOYSA-N

Data: 4 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 38921   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-alpha (Alpha-2) (Homo sapiens (Human))	BDBM38921 (MLS000056851 | N-(5-ethylsulfanyl-1,3,4-thiadiazol...) Show SMILES CCSc1nnc(NC(=O)c2ccccn2)s1 Show InChI InChI=1S/C10H10N4OS2/c1-2-16-10-14-13-9(17-10)12-8(15)7-5-3-4-6-11-7/h3-6H,2H2,1H3,(H,12,13,15)	PDB MMDB Reactome pathway KEGG B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q26Q1VNZ
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Steroidogenic factor 1 (Homo sapiens (Human))	BDBM38921 (MLS000056851 | N-(5-ethylsulfanyl-1,3,4-thiadiazol...) Show SMILES CCSc1nnc(NC(=O)c2ccccn2)s1 Show InChI InChI=1S/C10H10N4OS2/c1-2-16-10-14-13-9(17-10)12-8(15)7-5-3-4-6-11-7/h3-6H,2H2,1H3,(H,12,13,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>3.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2319T8T
					More data for this Ligand-Target Pair
Type-1 angiotensin II receptor (Homo sapiens (Human))	BDBM38921 (MLS000056851 | N-(5-ethylsulfanyl-1,3,4-thiadiazol...) Show SMILES CCSc1nnc(NC(=O)c2ccccn2)s1 Show InChI InChI=1S/C10H10N4OS2/c1-2-16-10-14-13-9(17-10)12-8(15)7-5-3-4-6-11-7/h3-6H,2H2,1H3,(H,12,13,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2CJ8BXT
					More data for this Ligand-Target Pair
Vacuolar aminopeptidase 1 (Saccharomyces cerevisiae)	BDBM38921 (MLS000056851 | N-(5-ethylsulfanyl-1,3,4-thiadiazol...) Show SMILES CCSc1nnc(NC(=O)c2ccccn2)s1 Show InChI InChI=1S/C10H10N4OS2/c1-2-16-10-14-13-9(17-10)12-8(15)7-5-3-4-6-11-7/h3-6H,2H2,1H3,(H,12,13,15)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.03E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q21R6P02
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM38921 (MLS000056851 | N-(5-ethylsulfanyl-1,3,4-thiadiazol...) Show SMILES CCSc1nnc(NC(=O)c2ccccn2)s1 Show InChI InChI=1S/C10H10N4OS2/c1-2-16-10-14-13-9(17-10)12-8(15)7-5-3-4-6-11-7/h3-6H,2H2,1H3,(H,12,13,15)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford- Sanford-Burnham Medical Research Institute(SBMRI, San...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2MK6BBZ
					More data for this Ligand-Target Pair
Streptokinase A (Streptococcus pyogenes M1 GAS)	BDBM38921 (MLS000056851 | N-(5-ethylsulfanyl-1,3,4-thiadiazol...) Show SMILES CCSc1nnc(NC(=O)c2ccccn2)s1 Show InChI InChI=1S/C10H10N4OS2/c1-2-16-10-14-13-9(17-10)12-8(15)7-5-3-4-6-11-7/h3-6H,2H2,1H3,(H,12,13,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2736PBV
					More data for this Ligand-Target Pair