BDBM39146 3-chloranyl-1-(3,4-dichlorophenyl)-4-[4-[2-(2-hydroxyethyloxy)ethyl]piperazin-1-yl]pyrrole-2,5-dione::3-chloro-1-(3,4-dichlorophenyl)-4-(4-(2-(2-hydroxyethoxy)ethyl)piperazin-1-yl)-1H-pyrrole-2,5-dione::3-chloro-1-(3,4-dichlorophenyl)-4-[4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl]pyrrole-2,5-dione::3-chloro-1-(3,4-dichlorophenyl)-4-[4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-yl]pyrrole-2,5-dione::3-chloro-1-(3,4-dichlorophenyl)-4-[4-[2-(2-hydroxyethoxy)ethyl]piperazino]-3-pyrroline-2,5-quinone::CHEMBL1272154::MLS-0090856.0001::cid_16654652

SMILES: OCCOCCN1CCN(CC1)C1=C(Cl)C(=O)N(C1=O)c1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=CINFJKPJKCBEHV-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 39146   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bfl-1 (Mus musculus (Mouse))	BDBM39146 (3-chloranyl-1-(3,4-dichlorophenyl)-4-[4-[2-(2-hydr...) Show SMILES OCCOCCN1CCN(CC1)C1=C(Cl)C(=O)N(C1=O)c1ccc(Cl)c(Cl)c1 |c:13| Show InChI InChI=1S/C18H20Cl3N3O4/c19-13-2-1-12(11-14(13)20)24-17(26)15(21)16(18(24)27)23-5-3-22(4-6-23)7-9-28-10-8-25/h1-2,11,25H,3-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2X065GM
					More data for this Ligand-Target Pair
Bcl-2-related protein A1 (Homo sapiens (Human))	BDBM39146 (3-chloranyl-1-(3,4-dichlorophenyl)-4-[4-[2-(2-hydr...) Show SMILES OCCOCCN1CCN(CC1)C1=C(Cl)C(=O)N(C1=O)c1ccc(Cl)c(Cl)c1 |c:13| Show InChI InChI=1S/C18H20Cl3N3O4/c19-13-2-1-12(11-14(13)20)24-17(26)15(21)16(18(24)27)23-5-3-22(4-6-23)7-9-28-10-8-25/h1-2,11,25H,3-10H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Human BioMolecular Research Institute Curated by ChEMBL					Assay Description Inhibition of N-terminal FITC BH3 peptide binding to GST-tagged Bfl1 by time resolved-FRET assay				Bioorg Med Chem Lett 20: 6560-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.046 BindingDB Entry DOI: 10.7270/Q27D2VCZ
					More data for this Ligand-Target Pair
Bcl-2-related protein A1 (Homo sapiens (Human))	BDBM39146 (3-chloranyl-1-(3,4-dichlorophenyl)-4-[4-[2-(2-hydr...) Show SMILES OCCOCCN1CCN(CC1)C1=C(Cl)C(=O)N(C1=O)c1ccc(Cl)c(Cl)c1 |c:13| Show InChI InChI=1S/C18H20Cl3N3O4/c19-13-2-1-12(11-14(13)20)24-17(26)15(21)16(18(24)27)23-5-3-22(4-6-23)7-9-28-10-8-25/h1-2,11,25H,3-10H2	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Human BioMolecular Research Institute Curated by ChEMBL					Assay Description Inhibition of N-terminal FITC BH3 peptide binding to GST-tagged Bfl1 by fluorescence polarization assay				Bioorg Med Chem Lett 20: 6560-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.046 BindingDB Entry DOI: 10.7270/Q27D2VCZ
					More data for this Ligand-Target Pair
Bfl-1 (Mus musculus (Mouse))	BDBM39146 (3-chloranyl-1-(3,4-dichlorophenyl)-4-[4-[2-(2-hydr...) Show SMILES OCCOCCN1CCN(CC1)C1=C(Cl)C(=O)N(C1=O)c1ccc(Cl)c(Cl)c1 |c:13| Show InChI InChI=1S/C18H20Cl3N3O4/c19-13-2-1-12(11-14(13)20)24-17(26)15(21)16(18(24)27)23-5-3-22(4-6-23)7-9-28-10-8-25/h1-2,11,25H,3-10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (San Diego, CA) NIH Molecular Libraries Screening Cen...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2K072NW
					More data for this Ligand-Target Pair