BDBM3927 5-Substituted 1-Phenylbenzimidazole 16::5-[2-(N,N-Dimethylamino)ethoxy]-1-phenylbenzimidazole Dihydrochloride::dimethyl({2-[(1-phenyl-1H-1,3-benzodiazol-5-yl)oxy]ethyl})amine

SMILES: CN(C)CCOc1ccc2n(cnc2c1)-c1ccccc1

InChI Key: InChIKey=WKHHTMXHSFWCIX-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3927   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM3927 (5-Substituted 1-Phenylbenzimidazole 16 | 5-[2-(N,N...) Show SMILES CN(C)CCOc1ccc2n(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C17H19N3O/c1-19(2)10-11-21-15-8-9-17-16(12-15)18-13-20(17)14-6-4-3-5-7-14/h3-9,12-13H,10-11H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	7.4	25
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 42: 2373-82 (1999) Article DOI: 10.1021/jm980658b BindingDB Entry DOI: 10.7270/Q2W957B2
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM3927 (5-Substituted 1-Phenylbenzimidazole 16 | 5-[2-(N,N...) Show SMILES CN(C)CCOc1ccc2n(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C17H19N3O/c1-19(2)10-11-21-15-8-9-17-16(12-15)18-13-20(17)14-6-4-3-5-7-14/h3-9,12-13H,10-11H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 42: 2373-82 (1999) Article DOI: 10.1021/jm980658b BindingDB Entry DOI: 10.7270/Q2W957B2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM3927 (5-Substituted 1-Phenylbenzimidazole 16 | 5-[2-(N,N...) Show SMILES CN(C)CCOc1ccc2n(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C17H19N3O/c1-19(2)10-11-21-15-8-9-17-16(12-15)18-13-20(17)14-6-4-3-5-7-14/h3-9,12-13H,10-11H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 42: 2373-82 (1999) Article DOI: 10.1021/jm980658b BindingDB Entry DOI: 10.7270/Q2W957B2
					More data for this Ligand-Target Pair