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SMILES: Fc1ccc(cc1)-c1c2c(CCNC2=O)n(Cc2ccccc2C#N)c1-c1ccncc1

InChI Key: InChIKey=BCUGBIIYLCGCSK-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 392870   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Receptor-interacting serine/threonine-protein kinase 3


(Homo sapiens (Human))		BDBM392870
PNG
(US10301306, Example 68)
Show SMILES Fc1ccc(cc1)-c1c2c(CCNC2=O)n(Cc2ccccc2C#N)c1-c1ccncc1
Show InChI InChI=1S/C26H19FN4O/c27-21-7-5-17(6-8-21)23-24-22(11-14-30-26(24)32)31(25(23)18-9-12-29-13-10-18)16-20-4-2-1-3-19(20)15-28/h1-10,12-13H,11,14,16H2,(H,30,32)
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n/an/a<30n/an/an/an/an/an/a



GSK



Assay Description
The assays were performed in black 1536-well plates. The final assay volume of 2 μl contained a mixture of a fluorescently labeled HTRF probe, T...

Bioorg Med Chem Lett 18: 5018-22 (2008)


BindingDB Entry DOI: 10.7270/Q2M90C19
More data for this
Ligand-Target Pair