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SMILES: CC(C)(C)CCn1c2CCNC(=O)c2c(c1-c1ccncc1)-c1ccc(F)cc1

InChI Key: InChIKey=CPQMKUJGUCFBPY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 392877   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Receptor-interacting serine/threonine-protein kinase 3


(Homo sapiens (Human))		BDBM392877
PNG
(US10301306, Example 75)
Show SMILES CC(C)(C)CCn1c2CCNC(=O)c2c(c1-c1ccncc1)-c1ccc(F)cc1
Show InChI InChI=1S/C24H26FN3O/c1-24(2,3)11-15-28-19-10-14-27-23(29)21(19)20(16-4-6-18(25)7-5-16)22(28)17-8-12-26-13-9-17/h4-9,12-13H,10-11,14-15H2,1-3H3,(H,27,29)
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n/an/a<30n/an/an/an/an/an/a



GSK



Assay Description
The assays were performed in black 1536-well plates. The final assay volume of 2 μl contained a mixture of a fluorescently labeled HTRF probe, T...

Bioorg Med Chem Lett 18: 5018-22 (2008)


BindingDB Entry DOI: 10.7270/Q2M90C19
More data for this
Ligand-Target Pair