BDBM392966 US10301306, Example 164

SMILES: Cc1ccc(s1)-c1c2c(CCNC2=O)n(Cc2ccc(Cl)cc2F)c1-c1ccncc1

InChI Key: InChIKey=FLQLRIHVSQGADD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 392966   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-interacting serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM392966 (US10301306, Example 164) Show SMILES Cc1ccc(s1)-c1c2c(CCNC2=O)n(Cc2ccc(Cl)cc2F)c1-c1ccncc1 Show InChI InChI=1S/C24H19ClFN3OS/c1-14-2-5-20(31-14)22-21-19(8-11-28-24(21)30)29(23(22)15-6-9-27-10-7-15)13-16-3-4-17(25)12-18(16)26/h2-7,9-10,12H,8,11,13H2,1H3,(H,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The assays were performed in black 1536-well plates. The final assay volume of 2 μl contained a mixture of a fluorescently labeled HTRF probe, T...				Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2M90C19
					More data for this Ligand-Target Pair