BDBM3930 4-{2-[(1-phenyl-1H-1,3-benzodiazol-5-yl)oxy]ethyl}morpholine::5-Substituted 1-Phenylbenzimidazole 19::5-[2-(4-Morpholino)ethoxy]-1-phenylbenzimidazole Dihydrochloride

SMILES: C(CN1CCOCC1)Oc1ccc2n(cnc2c1)-c1ccccc1

InChI Key: InChIKey=MGIAPSWVYILGFG-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3930   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM3930 (4-{2-[(1-phenyl-1H-1,3-benzodiazol-5-yl)oxy]ethyl}...) Show SMILES C(CN1CCOCC1)Oc1ccc2n(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C19H21N3O2/c1-2-4-16(5-3-1)22-15-20-18-14-17(6-7-19(18)22)24-13-10-21-8-11-23-12-9-21/h1-7,14-15H,8-13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	7.4	25
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 42: 2373-82 (1999) Article DOI: 10.1021/jm980658b BindingDB Entry DOI: 10.7270/Q2W957B2
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM3930 (4-{2-[(1-phenyl-1H-1,3-benzodiazol-5-yl)oxy]ethyl}...) Show SMILES C(CN1CCOCC1)Oc1ccc2n(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C19H21N3O2/c1-2-4-16(5-3-1)22-15-20-18-14-17(6-7-19(18)22)24-13-10-21-8-11-23-12-9-21/h1-7,14-15H,8-13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 42: 2373-82 (1999) Article DOI: 10.1021/jm980658b BindingDB Entry DOI: 10.7270/Q2W957B2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM3930 (4-{2-[(1-phenyl-1H-1,3-benzodiazol-5-yl)oxy]ethyl}...) Show SMILES C(CN1CCOCC1)Oc1ccc2n(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C19H21N3O2/c1-2-4-16(5-3-1)22-15-20-18-14-17(6-7-19(18)22)24-13-10-21-8-11-23-12-9-21/h1-7,14-15H,8-13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 42: 2373-82 (1999) Article DOI: 10.1021/jm980658b BindingDB Entry DOI: 10.7270/Q2W957B2
					More data for this Ligand-Target Pair