BDBM3932 4-{4-[(1-phenyl-1H-1,3-benzodiazol-5-yl)oxy]butyl}morpholine::5-Substituted 1-Phenylbenzimidazole 21::5-[4-(4-Morpholino)butoxy]-1]phenylbenzimidazole Dihydrochloride

SMILES: C(CCN1CCOCC1)COc1ccc2n(cnc2c1)-c1ccccc1

InChI Key: InChIKey=MMCPIFMHHYLZBY-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3932   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM3932 (4-{4-[(1-phenyl-1H-1,3-benzodiazol-5-yl)oxy]butyl}...) Show SMILES C(CCN1CCOCC1)COc1ccc2n(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C21H25N3O2/c1-2-6-18(7-3-1)24-17-22-20-16-19(8-9-21(20)24)26-13-5-4-10-23-11-14-25-15-12-23/h1-3,6-9,16-17H,4-5,10-15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	7.4	25
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 42: 2373-82 (1999) Article DOI: 10.1021/jm980658b BindingDB Entry DOI: 10.7270/Q2W957B2
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM3932 (4-{4-[(1-phenyl-1H-1,3-benzodiazol-5-yl)oxy]butyl}...) Show SMILES C(CCN1CCOCC1)COc1ccc2n(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C21H25N3O2/c1-2-6-18(7-3-1)24-17-22-20-16-19(8-9-21(20)24)26-13-5-4-10-23-11-14-25-15-12-23/h1-3,6-9,16-17H,4-5,10-15H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 42: 2373-82 (1999) Article DOI: 10.1021/jm980658b BindingDB Entry DOI: 10.7270/Q2W957B2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM3932 (4-{4-[(1-phenyl-1H-1,3-benzodiazol-5-yl)oxy]butyl}...) Show SMILES C(CCN1CCOCC1)COc1ccc2n(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C21H25N3O2/c1-2-6-18(7-3-1)24-17-22-20-16-19(8-9-21(20)24)26-13-5-4-10-23-11-14-25-15-12-23/h1-3,6-9,16-17H,4-5,10-15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 42: 2373-82 (1999) Article DOI: 10.1021/jm980658b BindingDB Entry DOI: 10.7270/Q2W957B2
					More data for this Ligand-Target Pair