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SMILES: Sc1ccc2n(cnc2c1)-c1ccccc1

InChI Key: InChIKey=QJMFHEHQAWFOPG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3934   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM3934 (1-phenyl-1H-1,3-benzodiazole-5-thiol | 5-Mercapto-...) Show SMILES Sc1ccc2n(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C13H10N2S/c16-11-6-7-13-12(8-11)14-9-15(13)10-4-2-1-3-5-10/h1-9,16H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	7.4	25
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 42: 2373-82 (1999) Article DOI: 10.1021/jm980658b BindingDB Entry DOI: 10.7270/Q2W957B2
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM3934 (1-phenyl-1H-1,3-benzodiazole-5-thiol | 5-Mercapto-...) Show SMILES Sc1ccc2n(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C13H10N2S/c16-11-6-7-13-12(8-11)14-9-15(13)10-4-2-1-3-5-10/h1-9,16H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 42: 2373-82 (1999) Article DOI: 10.1021/jm980658b BindingDB Entry DOI: 10.7270/Q2W957B2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM3934 (1-phenyl-1H-1,3-benzodiazole-5-thiol | 5-Mercapto-...) Show SMILES Sc1ccc2n(cnc2c1)-c1ccccc1 Show InChI InChI=1S/C13H10N2S/c16-11-6-7-13-12(8-11)14-9-15(13)10-4-2-1-3-5-10/h1-9,16H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 42: 2373-82 (1999) Article DOI: 10.1021/jm980658b BindingDB Entry DOI: 10.7270/Q2W957B2
					More data for this Ligand-Target Pair