BDBM3946 5,6-Dimethoxy-1-phenylbenzimidazole Hydrochloride::5,6-dimethoxy-1-phenyl-1H-1,3-benzodiazole::5-Substituted 1-Phenylbenzimidazole 35

SMILES: COc1cc2ncn(-c3ccccc3)c2cc1OC

InChI Key: InChIKey=DQTIAPJPNNWWDC-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3946   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM3946 (5,6-Dimethoxy-1-phenylbenzimidazole Hydrochloride ...) Show SMILES COc1cc2ncn(-c3ccccc3)c2cc1OC Show InChI InChI=1S/C15H14N2O2/c1-18-14-8-12-13(9-15(14)19-2)17(10-16-12)11-6-4-3-5-7-11/h3-10H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 42: 2373-82 (1999) Article DOI: 10.1021/jm980658b BindingDB Entry DOI: 10.7270/Q2W957B2
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM3946 (5,6-Dimethoxy-1-phenylbenzimidazole Hydrochloride ...) Show SMILES COc1cc2ncn(-c3ccccc3)c2cc1OC Show InChI InChI=1S/C15H14N2O2/c1-18-14-8-12-13(9-15(14)19-2)17(10-16-12)11-6-4-3-5-7-11/h3-10H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 42: 2373-82 (1999) Article DOI: 10.1021/jm980658b BindingDB Entry DOI: 10.7270/Q2W957B2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM3946 (5,6-Dimethoxy-1-phenylbenzimidazole Hydrochloride ...) Show SMILES COc1cc2ncn(-c3ccccc3)c2cc1OC Show InChI InChI=1S/C15H14N2O2/c1-18-14-8-12-13(9-15(14)19-2)17(10-16-12)11-6-4-3-5-7-11/h3-10H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 42: 2373-82 (1999) Article DOI: 10.1021/jm980658b BindingDB Entry DOI: 10.7270/Q2W957B2
					More data for this Ligand-Target Pair