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SMILES: COC(=O)c1cc2n(cnc2cc1OC)-c1ccccc1

InChI Key: InChIKey=AIARRPNZZRCXGD-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 3953   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM3953 (5-Substituted 1-Phenylbenzimidazole 42 | Methyl 5-...) Show SMILES COC(=O)c1cc2n(cnc2cc1OC)-c1ccccc1 Show InChI InChI=1S/C16H14N2O3/c1-20-15-9-13-14(8-12(15)16(19)21-2)18(10-17-13)11-6-4-3-5-7-11/h3-10H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 42: 2373-82 (1999) Article DOI: 10.1021/jm980658b BindingDB Entry DOI: 10.7270/Q2W957B2
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM3953 (5-Substituted 1-Phenylbenzimidazole 42 | Methyl 5-...) Show SMILES COC(=O)c1cc2n(cnc2cc1OC)-c1ccccc1 Show InChI InChI=1S/C16H14N2O3/c1-20-15-9-13-14(8-12(15)16(19)21-2)18(10-17-13)11-6-4-3-5-7-11/h3-10H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 42: 2373-82 (1999) Article DOI: 10.1021/jm980658b BindingDB Entry DOI: 10.7270/Q2W957B2
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM3953 (5-Substituted 1-Phenylbenzimidazole 42 | Methyl 5-...) Show SMILES COC(=O)c1cc2n(cnc2cc1OC)-c1ccccc1 Show InChI InChI=1S/C16H14N2O3/c1-20-15-9-13-14(8-12(15)16(19)21-2)18(10-17-13)11-6-4-3-5-7-11/h3-10H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 42: 2373-82 (1999) Article DOI: 10.1021/jm980658b BindingDB Entry DOI: 10.7270/Q2W957B2
					More data for this Ligand-Target Pair