BDBM39847 Amide and sulfonamide derivatives, 31
SMILES: OB(O)c1cccc(NS(=O)(=O)c2ccc(CNC(=O)c3ccc(Cl)cc3)s2)c1
InChI Key: InChIKey=VZCYKNKTQUEGTL-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-lactamase AmpC (Escherichia coli) | BDBM39847![]() (Amide and sulfonamide derivatives, 31) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | 860 | n/a | n/a | n/a | n/a | n/a | n/a | 7.0 | n/a |
Northwestern University | Assay Description Inhibition assay against beta lactamase enzymes. | Chem Biol 8: 593-611 (2001) Article DOI: 10.1016/S1074-5521(01)00034-5 BindingDB Entry DOI: 10.7270/Q27M06BZ | |||||||||||
More data for this Ligand-Target Pair |