BDBM40034 MLS000093573::N-(3-keto-4-methyl-1,4-benzothiazin-6-yl)-4-piperidino-piperidine-1-carboxamide::N-(4-methyl-3-oxidanylidene-1,4-benzothiazin-6-yl)-4-piperidin-1-yl-piperidine-1-carboxamide::N-(4-methyl-3-oxo-1,4-benzothiazin-6-yl)-4-(1-piperidinyl)-1-piperidinecarboxamide::N-(4-methyl-3-oxo-1,4-benzothiazin-6-yl)-4-piperidin-1-ylpiperidine-1-carboxamide::N-(4-methyl-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-6-yl)-1,4'-bipiperidine-1'-carboxamide::SMR000029191::cid_3241667

SMILES: CN1C(=O)CSc2ccc(NC(=O)N3CCC(CC3)N3CCCCC3)cc12

InChI Key: InChIKey=GLAMRQHQNIRTNJ-UHFFFAOYSA-N

Data: 4 IC50  5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 40034   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM40034 (MLS000093573 | N-(3-keto-4-methyl-1,4-benzothiazin...) Show SMILES CN1C(=O)CSc2ccc(NC(=O)N3CCC(CC3)N3CCCCC3)cc12 Show InChI InChI=1S/C20H28N4O2S/c1-22-17-13-15(5-6-18(17)27-14-19(22)25)21-20(26)24-11-7-16(8-12-24)23-9-3-2-4-10-23/h5-6,13,16H,2-4,7-12,14H2,1H3,(H,21,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2QJ7FQ3
					More data for this Ligand-Target Pair
RGS7 (Homo sapiens (Human))	BDBM40034 (MLS000093573 | N-(3-keto-4-methyl-1,4-benzothiazin...) Show SMILES CN1C(=O)CSc2ccc(NC(=O)N3CCC(CC3)N3CCCCC3)cc12 Show InChI InChI=1S/C20H28N4O2S/c1-22-17-13-15(5-6-18(17)27-14-19(22)25)21-20(26)24-11-7-16(8-12-24)23-9-3-2-4-10-23/h5-6,13,16H,2-4,7-12,14H2,1H3,(H,21,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2PV6HS7
					More data for this Ligand-Target Pair
G protein signalling regulator 19 (Homo sapiens (Human))	BDBM40034 (MLS000093573 | N-(3-keto-4-methyl-1,4-benzothiazin...) Show SMILES CN1C(=O)CSc2ccc(NC(=O)N3CCC(CC3)N3CCCCC3)cc12 Show InChI InChI=1S/C20H28N4O2S/c1-22-17-13-15(5-6-18(17)27-14-19(22)25)21-20(26)24-11-7-16(8-12-24)23-9-3-2-4-10-23/h5-6,13,16H,2-4,7-12,14H2,1H3,(H,21,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2K35S27
					More data for this Ligand-Target Pair
regulator of G-protein signalling 16 (Homo sapiens (Human))	BDBM40034 (MLS000093573 | N-(3-keto-4-methyl-1,4-benzothiazin...) Show SMILES CN1C(=O)CSc2ccc(NC(=O)N3CCC(CC3)N3CCCCC3)cc12 Show InChI InChI=1S/C20H28N4O2S/c1-22-17-13-15(5-6-18(17)27-14-19(22)25)21-20(26)24-11-7-16(8-12-24)23-9-3-2-4-10-23/h5-6,13,16H,2-4,7-12,14H2,1H3,(H,21,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2FB51BW
					More data for this Ligand-Target Pair
regulator of G-protein signaling 4 (Homo sapiens (Human))	BDBM40034 (MLS000093573 | N-(3-keto-4-methyl-1,4-benzothiazin...) Show SMILES CN1C(=O)CSc2ccc(NC(=O)N3CCC(CC3)N3CCCCC3)cc12 Show InChI InChI=1S/C20H28N4O2S/c1-22-17-13-15(5-6-18(17)27-14-19(22)25)21-20(26)24-11-7-16(8-12-24)23-9-3-2-4-10-23/h5-6,13,16H,2-4,7-12,14H2,1H3,(H,21,26)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2F76B0G
					More data for this Ligand-Target Pair
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM40034 (MLS000093573 | N-(3-keto-4-methyl-1,4-benzothiazin...) Show SMILES CN1C(=O)CSc2ccc(NC(=O)N3CCC(CC3)N3CCCCC3)cc12 Show InChI InChI=1S/C20H28N4O2S/c1-22-17-13-15(5-6-18(17)27-14-19(22)25)21-20(26)24-11-7-16(8-12-24)23-9-3-2-4-10-23/h5-6,13,16H,2-4,7-12,14H2,1H3,(H,21,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2CF9NHH
					More data for this Ligand-Target Pair
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM40034 (MLS000093573 | N-(3-keto-4-methyl-1,4-benzothiazin...) Show SMILES CN1C(=O)CSc2ccc(NC(=O)N3CCC(CC3)N3CCCCC3)cc12 Show InChI InChI=1S/C20H28N4O2S/c1-22-17-13-15(5-6-18(17)27-14-19(22)25)21-20(26)24-11-7-16(8-12-24)23-9-3-2-4-10-23/h5-6,13,16H,2-4,7-12,14H2,1H3,(H,21,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	6.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q2WD3Z0J
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 8 (Homo sapiens (Human))	BDBM40034 (MLS000093573 | N-(3-keto-4-methyl-1,4-benzothiazin...) Show SMILES CN1C(=O)CSc2ccc(NC(=O)N3CCC(CC3)N3CCCCC3)cc12 Show InChI InChI=1S/C20H28N4O2S/c1-22-17-13-15(5-6-18(17)27-14-19(22)25)21-20(26)24-11-7-16(8-12-24)23-9-3-2-4-10-23/h5-6,13,16H,2-4,7-12,14H2,1H3,(H,21,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2TM78JD
					More data for this Ligand-Target Pair
Estradiol receptor beta (ERβ) (Homo sapiens (Human))	BDBM40034 (MLS000093573 | N-(3-keto-4-methyl-1,4-benzothiazin...) Show SMILES CN1C(=O)CSc2ccc(NC(=O)N3CCC(CC3)N3CCCCC3)cc12 Show InChI InChI=1S/C20H28N4O2S/c1-22-17-13-15(5-6-18(17)27-14-19(22)25)21-20(26)24-11-7-16(8-12-24)23-9-3-2-4-10-23/h5-6,13,16H,2-4,7-12,14H2,1H3,(H,21,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	7.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2CF9NHH
					More data for this Ligand-Target Pair