BDBM4064 8-Methyl-2-phenylamino-6-thiophene-3-yl-8H-pyrido-[2,3-d]pyrimidin-7-one::8-methyl-2-(phenylamino)-6-(thiophen-3-yl)-7H,8H-pyrido[2,3-d]pyrimidin-7-one::pyrido[2,3-d]pyrimidin-7-one deriv. 25

SMILES: Cn1c2nc(Nc3ccccc3)ncc2cc(-c2ccsc2)c1=O

InChI Key: InChIKey=XMOUFRISTWXUBM-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 4064   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM4064 (8-Methyl-2-phenylamino-6-thiophene-3-yl-8H-pyrido-...) Show SMILES Cn1c2nc(Nc3ccccc3)ncc2cc(-c2ccsc2)c1=O Show InChI InChI=1S/C18H14N4OS/c1-22-16-13(9-15(17(22)23)12-7-8-24-11-12)10-19-18(21-16)20-14-5-3-2-4-6-14/h2-11H,1H3,(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 41: 4365-77 (1998) Article DOI: 10.1021/jm980398y BindingDB Entry DOI: 10.7270/Q2CC0XWN
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4064 (8-Methyl-2-phenylamino-6-thiophene-3-yl-8H-pyrido-...) Show SMILES Cn1c2nc(Nc3ccccc3)ncc2cc(-c2ccsc2)c1=O Show InChI InChI=1S/C18H14N4OS/c1-22-16-13(9-15(17(22)23)12-7-8-24-11-12)10-19-18(21-16)20-14-5-3-2-4-6-14/h2-11H,1H3,(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 41: 4365-77 (1998) Article DOI: 10.1021/jm980398y BindingDB Entry DOI: 10.7270/Q2CC0XWN
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM4064 (8-Methyl-2-phenylamino-6-thiophene-3-yl-8H-pyrido-...) Show SMILES Cn1c2nc(Nc3ccccc3)ncc2cc(-c2ccsc2)c1=O Show InChI InChI=1S/C18H14N4OS/c1-22-16-13(9-15(17(22)23)12-7-8-24-11-12)10-19-18(21-16)20-14-5-3-2-4-6-14/h2-11H,1H3,(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 41: 4365-77 (1998) Article DOI: 10.1021/jm980398y BindingDB Entry DOI: 10.7270/Q2CC0XWN
					More data for this Ligand-Target Pair