BDBM42131 CEFACLOR::MLS000069617::SMR000058250::cid_51039
SMILES: N[C@@H](C(=O)N[C@H]1[C@H]2SCC(Cl)=C(N2C1=O)C(O)=O)c1ccccc1
InChI Key: InChIKey=QYIYFLOTGYLRGG-GPCCPHFNSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Solute carrier family 15 member 2 (Homo sapiens (Human)) | BDBM42131 (CEFACLOR | MLS000069617 | SMR000058250 | cid_51039) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Milano Curated by ChEMBL | Assay Description Binding affinity to human PepT2 in SKTP cells | Bioorg Med Chem 19: 4544-51 (2011) Article DOI: 10.1016/j.bmc.2011.06.027 BindingDB Entry DOI: 10.7270/Q2MP549P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligopeptide transporter, kidney isoform (Rattus norvegicus) | BDBM42131 (CEFACLOR | MLS000069617 | SMR000058250 | cid_51039) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biozentrum of the Martin-Luther-University Halle-Wittenberg Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in SKPT cells | Eur J Pharm Biopharm 59: 17-24 (2004) Article DOI: 10.1016/j.ejpb.2004.07.008 BindingDB Entry DOI: 10.7270/Q2TT4S7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligopeptide transporter small intestine isoform (Homo sapiens (Human)) | BDBM42131 (CEFACLOR | MLS000069617 | SMR000058250 | cid_51039) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | >1.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Biozentrum of the Martin-Luther-University Halle-Wittenberg Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in Caco-2 cells | Eur J Pharm Biopharm 59: 17-24 (2004) Article DOI: 10.1016/j.ejpb.2004.07.008 BindingDB Entry DOI: 10.7270/Q2TT4S7H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligopeptide transporter small intestine isoform (Homo sapiens (Human)) | BDBM42131 (CEFACLOR | MLS000069617 | SMR000058250 | cid_51039) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | >1.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Martin-Luther-University Halle-Wittenberg Curated by ChEMBL | Assay Description Binding affinity against membrane transport protein PEPT1 in human Caco-2 cells | J Med Chem 48: 4410-9 (2005) Article DOI: 10.1021/jm048982w BindingDB Entry DOI: 10.7270/Q2Q24116 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1 (Homo sapiens (Human)) | BDBM42131 (CEFACLOR | MLS000069617 | SMR000058250 | cid_51039) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | 7.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C... | PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2V986KM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Solute carrier family 22 member 8 (Homo sapiens (Human)) | BDBM42131 (CEFACLOR | MLS000069617 | SMR000058250 | cid_51039) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Wilkes University Curated by ChEMBL | Assay Description Inhibition of human OAT3 using estrone-3-sulfate as substrate | Drug Metab Dispos 41: 791-800 (2013) Article DOI: 10.1124/dmd.112.049569 BindingDB Entry DOI: 10.7270/Q2TF003W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligopeptide transporter small intestine isoform (Homo sapiens (Human)) | BDBM42131 (CEFACLOR | MLS000069617 | SMR000058250 | cid_51039) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | 8.20E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Michigan Curated by ChEMBL | Assay Description TP_TRANSPORTER: inhibition of Gly-Sar uptake (Gly-Sar: 20 uM) in PEPT1-expressing CHO cells | J Pharm Sci 88: 347-50 (1999) Article DOI: 10.1021/js980132e BindingDB Entry DOI: 10.7270/Q22V2H6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bile salt export pump (Homo sapiens (Human)) | BDBM42131 (CEFACLOR | MLS000069617 | SMR000058250 | cid_51039) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc Curated by ChEMBL | Assay Description Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ... | Toxicol Sci 136: 216-41 (2013) BindingDB Entry DOI: 10.7270/Q2JM2D2D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Multidrug resistance-associated protein 4 (Homo sapiens (Human)) | BDBM42131 (CEFACLOR | MLS000069617 | SMR000058250 | cid_51039) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc Curated by ChEMBL | Assay Description Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and... | Toxicol Sci 136: 216-41 (2013) BindingDB Entry DOI: 10.7270/Q2JM2D2D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Canalicular multispecific organic anion transporter 1 (Homo sapiens (Human)) | BDBM42131 (CEFACLOR | MLS000069617 | SMR000058250 | cid_51039) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc Curated by ChEMBL | Assay Description Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and... | Toxicol Sci 136: 216-41 (2013) BindingDB Entry DOI: 10.7270/Q2JM2D2D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
streptokinase A precursor (Streptococcus pyogenes M1 GAS) | BDBM42131 (CEFACLOR | MLS000069617 | SMR000058250 | cid_51039) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a |
Broad Institute Curated by PubChem BioAssay | Assay Description Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2736PBV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
YopH (Yersinia enterocolitica) | BDBM42131 (CEFACLOR | MLS000069617 | SMR000058250 | cid_51039) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay | Assay Description Yersinia pestis is the causal agent of the bubonic plague and, although modern antibiotics are extremely effective against the malady, the plague rem... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2C24TVC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Canalicular multispecific organic anion transporter 2 (Homo sapiens (Human)) | BDBM42131 (CEFACLOR | MLS000069617 | SMR000058250 | cid_51039) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.33E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc Curated by ChEMBL | Assay Description Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ... | Toxicol Sci 136: 216-41 (2013) BindingDB Entry DOI: 10.7270/Q2JM2D2D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
YopH (Yersinia enterocolitica) | BDBM42131 (CEFACLOR | MLS000069617 | SMR000058250 | cid_51039) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay | Assay Description Yersinia pestis is the causal agent of the bubonic plague and, although modern antibiotics are extremely effective against the malady, the plague rem... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2794330 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
YopH (Yersinia enterocolitica) | BDBM42131 (CEFACLOR | MLS000069617 | SMR000058250 | cid_51039) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Molecular Library Screening Center Curated by PubChem BioAssay | Assay Description Yersinia pestis is the causal agent of the bubonic plague and, although modern antibiotics are extremely effective against the malady, the plague rem... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2GT5KKS | |||||||||||
More data for this Ligand-Target Pair |