BDBM43082 MLS000589154::N-(4-Chloro-phenyl)-2-(3-ethyl-4-oxo-3,4,6,7,8,9-hexahydro-pyrimido[4,5-b]quinolin-2-ylsulfanyl)-acetamide::N-(4-chlorophenyl)-2-[(3-ethyl-4-keto-6,7,8,9-tetrahydropyrimido[4,5-b]quinolin-2-yl)thio]acetamide::N-(4-chlorophenyl)-2-[(3-ethyl-4-oxidanylidene-6,7,8,9-tetrahydropyrimido[4,5-b]quinolin-2-yl)sulfanyl]ethanamide::N-(4-chlorophenyl)-2-[(3-ethyl-4-oxo-6,7,8,9-tetrahydropyrimido[4,5-b]quinolin-2-yl)sulfanyl]acetamide::N-(4-chlorophenyl)-2-[(3-ethyl-4-oxo-6,7,8,9-tetrahydropyrimido[4,5-b]quinolin-2-yl)thio]acetamide::SMR000219771::cid_2012194

SMILES: CCn1c(SCC(=O)Nc2ccc(Cl)cc2)nc2nc3CCCCc3cc2c1=O

InChI Key: InChIKey=SFXVZNHMVKVIOO-UHFFFAOYSA-N

Data: 5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 43082   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor coactivator 1 (Homo sapiens (Human))	BDBM43082 (MLS000589154 | N-(4-Chloro-phenyl)-2-(3-ethyl-4-ox...) Show SMILES CCn1c(SCC(=O)Nc2ccc(Cl)cc2)nc2nc3CCCCc3cc2c1=O Show InChI InChI=1S/C21H21ClN4O2S/c1-2-26-20(28)16-11-13-5-3-4-6-17(13)24-19(16)25-21(26)29-12-18(27)23-15-9-7-14(22)8-10-15/h7-11H,2-6,12H2,1H3,(H,23,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>7.94E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2FT8JGV
					More data for this Ligand-Target Pair
Nuclear receptor coactivator 3 (Homo sapiens (Human))	BDBM43082 (MLS000589154 | N-(4-Chloro-phenyl)-2-(3-ethyl-4-ox...) Show SMILES CCn1c(SCC(=O)Nc2ccc(Cl)cc2)nc2nc3CCCCc3cc2c1=O Show InChI InChI=1S/C21H21ClN4O2S/c1-2-26-20(28)16-11-13-5-3-4-6-17(13)24-19(16)25-21(26)29-12-18(27)23-15-9-7-14(22)8-10-15/h7-11H,2-6,12H2,1H3,(H,23,27)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>7.94E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center http://molscreen.florida.scripps.edu/ Center Affiliation: The ...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2707ZV7
					More data for this Ligand-Target Pair
Solute carrier family 12 member 5 (Homo sapiens (Human))	BDBM43082 (MLS000589154 | N-(4-Chloro-phenyl)-2-(3-ethyl-4-ox...) Show SMILES CCn1c(SCC(=O)Nc2ccc(Cl)cc2)nc2nc3CCCCc3cc2c1=O Show InChI InChI=1S/C21H21ClN4O2S/c1-2-26-20(28)16-11-13-5-3-4-6-17(13)24-19(16)25-21(26)29-12-18(27)23-15-9-7-14(22)8-10-15/h7-11H,2-6,12H2,1H3,(H,23,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	4.55E+4	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Assay Provider: Eric Delpire Assay Provider Affliation: Vanderbilt University Gr...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2M32T6M
					More data for this Ligand-Target Pair
Nuclear receptor coactivator 2 (Homo sapiens (Human))	BDBM43082 (MLS000589154 | N-(4-Chloro-phenyl)-2-(3-ethyl-4-ox...) Show SMILES CCn1c(SCC(=O)Nc2ccc(Cl)cc2)nc2nc3CCCCc3cc2c1=O Show InChI InChI=1S/C21H21ClN4O2S/c1-2-26-20(28)16-11-13-5-3-4-6-17(13)24-19(16)25-21(26)29-12-18(27)23-15-9-7-14(22)8-10-15/h7-11H,2-6,12H2,1H3,(H,23,27)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>7.94E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2QZ28CS
					More data for this Ligand-Target Pair
Solute carrier family 12 member 5 (Homo sapiens (Human))	BDBM43082 (MLS000589154 | N-(4-Chloro-phenyl)-2-(3-ethyl-4-ox...) Show SMILES CCn1c(SCC(=O)Nc2ccc(Cl)cc2)nc2nc3CCCCc3cc2c1=O Show InChI InChI=1S/C21H21ClN4O2S/c1-2-26-20(28)16-11-13-5-3-4-6-17(13)24-19(16)25-21(26)29-12-18(27)23-15-9-7-14(22)8-10-15/h7-11H,2-6,12H2,1H3,(H,23,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	2.82E+4	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Assay Provider: Eric Delpire Assay Provider Affliation: Vanderbilt University Gr...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2TX3CSC
					More data for this Ligand-Target Pair