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SMILES: [#6]-[#8]-c1cc(\[#6]=[#6](/C#N)C#N)cc(Br)c1-[#8]

InChI Key: InChIKey=RMTVRMJDCJSEMW-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4334   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM4334
PNG
(2-[(3-bromo-4-hydroxy-5-methoxyphenyl)methylidene]...)
Show SMILES [#6]-[#8]-c1cc(\[#6]=[#6](/C#N)C#N)cc(Br)c1-[#8]
Show InChI InChI=1S/C11H7BrN2O2/c1-16-10-4-7(2-8(5-13)6-14)3-9(12)11(10)15/h2-4,15H,1H3
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UniChem

Similars
Article
PubMed
 5.00E+4 -5.80 1.53E+5n/an/an/an/a7.622



Hebrew University of Jerusalem



Assay Description
The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.

J Med Chem 32: 2344-52 (1989)


Article DOI: 10.1021/jm00130a020
BindingDB Entry DOI: 10.7270/Q2G44NHF
More data for this
Ligand-Target Pair