BDBM43447 (5Z)-1-[2-(4-fluorophenyl)ethyl]-5-[(E)-3-phenylprop-2-enylidene]-1,3-diazinane-2,4,6-trione::(5Z)-1-[2-(4-fluorophenyl)ethyl]-5-[(E)-3-phenylprop-2-enylidene]barbituric acid::1-[2-(4-fluorophenyl)ethyl]-5-(3-phenyl-2-propen-1-ylidene)-2,4,6(1H,3H,5H)-pyrimidinetrione::MLS000677107::SMR000270932::cid_1325216

SMILES: Fc1ccc(CCN2C(=O)NC(=O)\C(=C\C=C\c3ccccc3)C2=O)cc1

InChI Key: InChIKey=ZRCCDSAAMJJQCI-DFBITEFZSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 43447   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MDM2-MDMX (Homo sapiens (Human))	BDBM43447 ((5Z)-1-[2-(4-fluorophenyl)ethyl]-5-[(E)-3-phenylpr...) Show SMILES Fc1ccc(CCN2C(=O)NC(=O)\C(=C\C=C\c3ccccc3)C2=O)cc1 Show InChI InChI=1S/C21H17FN2O3/c22-17-11-9-16(10-12-17)13-14-24-20(26)18(19(25)23-21(24)27)8-4-7-15-5-2-1-3-6-15/h1-12H,13-14H2,(H,23,25,27)/b7-4+,18-8-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q21J984Z
					More data for this Ligand-Target Pair