BDBM43472 MLS000419411::N-(1,3-diketoisoindolin-5-yl)-2,3-dihydro-1,4-benzodioxin-3-carboxamide::N-(1,3-dioxo-5-isoindolyl)-2,3-dihydro-1,4-benzodioxin-3-carboxamide::N-(1,3-dioxoisoindol-5-yl)-2,3-dihydro-1,4-benzodioxine-3-carboxamide::N-[1,3-bis(oxidanylidene)isoindol-5-yl]-2,3-dihydro-1,4-benzodioxine-3-carboxamide::SMR000320163::cid_4641353

SMILES: O=C(Nc1ccc2C(=O)NC(=O)c2c1)C1COc2ccccc2O1

InChI Key: InChIKey=UTADGGLIHPQPNU-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 43472   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MDM2-MDMX (Homo sapiens (Human))	BDBM43472 (MLS000419411 | N-(1,3-diketoisoindolin-5-yl)-2,3-d...) Show SMILES O=C(Nc1ccc2C(=O)NC(=O)c2c1)C1COc2ccccc2O1 Show InChI InChI=1S/C17H12N2O5/c20-15-10-6-5-9(7-11(10)16(21)19-15)18-17(22)14-8-23-12-3-1-2-4-13(12)24-14/h1-7,14H,8H2,(H,18,22)(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	6.75E+3	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Brent Stockwell, Columbia University ML...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q21J984Z
					More data for this Ligand-Target Pair