BDBM43831 5-(4-fluorobenzyl)-4-keto-6,7-dihydropyrazolo[1,5-a]pyrazine-2-carboxylic acid methyl ester::5-[(4-fluorophenyl)methyl]-4-oxo-6,7-dihydropyrazolo[1,5-a]pyrazine-2-carboxylic acid methyl ester::Glucosamine derivative, 4::MLS000326913::SMR000179467::cid_1475682::methyl 5-(4-fluorobenzyl)-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate::methyl 5-[(4-fluorophenyl)methyl]-4-oxidanylidene-6,7-dihydropyrazolo[1,5-a]pyrazine-2-carboxylate::methyl 5-[(4-fluorophenyl)methyl]-4-oxo-6,7-dihydropyrazolo[1,5-a]pyrazine-2-carboxylate

SMILES: COC(=O)c1cc2C(=O)N(Cc3ccc(F)cc3)CCn2n1

InChI Key: InChIKey=YVFQWAXEZSQJBV-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 43831   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphotransferase (Trypanosoma brucei)	BDBM43831 (5-(4-fluorobenzyl)-4-keto-6,7-dihydropyrazolo[1,5-...) Show SMILES COC(=O)c1cc2C(=O)N(Cc3ccc(F)cc3)CCn2n1 Show InChI InChI=1S/C15H14FN3O3/c1-22-15(21)12-8-13-14(20)18(6-7-19(13)17-12)9-10-2-4-11(16)5-3-10/h2-5,8H,6-7,9H2,1H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	1.14E+5	-5.38	1.80E+6	n/a	n/a	n/a	n/a	n/a	25
Groupe de Chimie Organique Biologique, Laboratoire Synthése Physico-Chimie des Molécules d'Inérêt Biologique					Assay Description Competitive inhibition assay for glucosamine derivatives on hexokinase from trypanosoma brucei. The inhibition of hexokinase by compounds was measur...				Chem Biol 9: 839-47 (2002) Article DOI: 10.1016/S1074-5521(02)00169-2 BindingDB Entry DOI: 10.7270/Q2MC8XF1
					More data for this Ligand-Target Pair
DNA repair protein RAD51 homolog 1 (Homo sapiens (Human))	BDBM43831 (5-(4-fluorobenzyl)-4-keto-6,7-dihydropyrazolo[1,5-...) Show SMILES COC(=O)c1cc2C(=O)N(Cc3ccc(F)cc3)CCn2n1 Show InChI InChI=1S/C15H14FN3O3/c1-22-15(21)12-8-13-14(20)18(6-7-19(13)17-12)9-10-2-4-11(16)5-3-10/h2-5,8H,6-7,9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2BV7F1T
					More data for this Ligand-Target Pair