BDBM43843 (E)-3-(1-benzyl-3-pyridin-3-ylpyrazol-4-yl)prop-2-enoic acid::(E)-3-[1-(phenylmethyl)-3-(3-pyridinyl)-4-pyrazolyl]-2-propenoic acid::(E)-3-[1-(phenylmethyl)-3-pyridin-3-yl-pyrazol-4-yl]prop-2-enoic acid::(E)-3-[1-benzyl-3-(3-pyridyl)pyrazol-4-yl]acrylic acid::Acid, 25::MLS000773816::SMR000364660::cid_5940518

SMILES: OC(=O)\C=C\c1cn(Cc2ccccc2)nc1-c1cccnc1

InChI Key: InChIKey=OXIKLRTYAYRAOE-CMDGGOBGSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 43843   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA repair protein RAD51 homolog 1 (Homo sapiens (Human))	BDBM43843 ((E)-3-(1-benzyl-3-pyridin-3-ylpyrazol-4-yl)prop-2-...) Show SMILES OC(=O)\C=C\c1cn(Cc2ccccc2)nc1-c1cccnc1 Show InChI InChI=1S/C18H15N3O2/c22-17(23)9-8-16-13-21(12-14-5-2-1-3-6-14)20-18(16)15-7-4-10-19-11-15/h1-11,13H,12H2,(H,22,23)/b9-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2QN6558
					More data for this Ligand-Target Pair
HIV-1 protease (Human immunodeficiency virus)	BDBM43843 ((E)-3-(1-benzyl-3-pyridin-3-ylpyrazol-4-yl)prop-2-...) Show SMILES OC(=O)\C=C\c1cn(Cc2ccccc2)nc1-c1cccnc1 Show InChI InChI=1S/C18H15N3O2/c22-17(23)9-8-16-13-21(12-14-5-2-1-3-6-14)20-18(16)15-7-4-10-19-11-15/h1-11,13H,12H2,(H,22,23)/b9-8+	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	5.6	37
The Scripps Research Institute					Assay Description Inhibition of HIV-protease activity for selected acids at P3-P3' positions.				Chem Biol 9: 891-6 (2002) Article DOI: 10.1016/S1074-5521(02)00184-9 BindingDB Entry DOI: 10.7270/Q2GM85QP
					More data for this Ligand-Target Pair