BDBM43845 2-[(2-chlorophenyl)hydrazo]-2-(2-oxolanylmethylimino)acetic acid ethyl ester::2-[N''''-(2-chlorophenyl)hydrazino]-2-(tetrahydrofurfurylimino)acetic acid ethyl ester::2-[N''-(2-chlorophenyl)hydrazino]-2-(tetrahydrofurfurylimino)acetic acid ethyl ester::2-[N'-(2-chlorophenyl)hydrazino]-2-(tetrahydrofurfurylimino)acetic acid ethyl ester::Acid, 53::MLS001032911::SMR000363487::cid_4110203::ethyl 2-[2-(2-chlorophenyl)hydrazinyl]-2-(oxolan-2-ylmethylimino)acetate::ethyl 2-[2-(2-chlorophenyl)hydrazinyl]-2-(oxolan-2-ylmethylimino)ethanoate
SMILES: CCOC(=O)C(NNc1ccccc1Cl)=NCC1CCCO1
InChI Key: InChIKey=SFMPLSNCCXLXBZ-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA repair protein RAD51 homolog 1 (Homo sapiens (Human)) | BDBM43845 (2-[(2-chlorophenyl)hydrazo]-2-(2-oxolanylmethylimi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 5.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
PCMD Curated by PubChem BioAssay | Assay Description Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2QN6558 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HIV-1 protease (Human immunodeficiency virus) | BDBM43845 (2-[(2-chlorophenyl)hydrazo]-2-(2-oxolanylmethylimi...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | 5.6 | 37 |
The Scripps Research Institute | Assay Description Inhibition of HIV-protease activity for selected acids at P3-P3' positions. | Chem Biol 9: 891-6 (2002) Article DOI: 10.1016/S1074-5521(02)00184-9 BindingDB Entry DOI: 10.7270/Q2GM85QP | |||||||||||
More data for this Ligand-Target Pair |