BDBM43852 2-[4-(4-methylphenyl)-2-(2-pyridinyl)-5-thiazolyl]acetic acid::2-[4-(4-methylphenyl)-2-pyridin-2-yl-1,3-thiazol-5-yl]acetic acid::2-[4-(4-methylphenyl)-2-pyridin-2-yl-1,3-thiazol-5-yl]ethanoic acid::2-[4-(p-tolyl)-2-(2-pyridyl)thiazol-5-yl]acetic acid::AB-1::MLS000761246::SMR000369548::cid_2118147

SMILES: Cc1ccc(cc1)-c1nc(sc1CC(O)=O)-c1ccccn1

InChI Key: InChIKey=WFBZZYNOMFNULR-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 43852   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIV-1 protease (Human immunodeficiency virus)	BDBM43852 (2-[4-(4-methylphenyl)-2-(2-pyridinyl)-5-thiazolyl]...) Show SMILES Cc1ccc(cc1)-c1nc(sc1CC(O)=O)-c1ccccn1 Show InChI InChI=1S/C17H14N2O2S/c1-11-5-7-12(8-6-11)16-14(10-15(20)21)22-17(19-16)13-4-2-3-9-18-13/h2-9H,10H2,1H3,(H,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2	-12.3	n/a	n/a	n/a	n/a	n/a	5.6	37
The Scripps Research Institute					Assay Description Inhibition of HIV-protease activity for selected acids at P3-P3' positions.				Chem Biol 9: 891-6 (2002) Article DOI: 10.1016/S1074-5521(02)00184-9 BindingDB Entry DOI: 10.7270/Q2GM85QP
					More data for this Ligand-Target Pair
DNA repair protein RAD51 homolog 1 (Homo sapiens (Human))	BDBM43852 (2-[4-(4-methylphenyl)-2-(2-pyridinyl)-5-thiazolyl]...) Show SMILES Cc1ccc(cc1)-c1nc(sc1CC(O)=O)-c1ccccn1 Show InChI InChI=1S/C17H14N2O2S/c1-11-5-7-12(8-6-11)16-14(10-15(20)21)22-17(19-16)13-4-2-3-9-18-13/h2-9H,10H2,1H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
PCMD Curated by PubChem BioAssay					Assay Description Project Title: A screen for modulators of human Rad51, a key DNA repair protein Application Number: MH084119 Assay Submitter: Dr. Alex Mazin Submitte...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2QN6558
					More data for this Ligand-Target Pair