BDBM44021 (5Z)-3-(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyrazol-4-yl)-5-[(4-methylphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one::(5Z)-3-(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolyl)-5-[(4-methylphenyl)methylidene]-2-sulfanylidene-4-thiazolidinone::(5Z)-3-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-5-[(4-methylphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one::(5Z)-3-(3-keto-1,5-dimethyl-2-phenyl-3-pyrazolin-4-yl)-5-(4-methylbenzylidene)-2-thioxo-thiazolidin-4-one::3-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-5-(4-methylbenzylidene)-2-thioxo-1,3-thiazolidin-4-one::MLS000578746::SMR000186239::cid_1230208

SMILES: Cc1c(N2C(=S)S\C(=C/c3ccc(C)cc3)C2=O)c(=O)n(-c2ccccc2)n1C

InChI Key: InChIKey=RALQROGOXLZPPK-AQTBWJFISA-N

Data: 1 IC50  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 44021   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
electroneutral potassium-chloride cotransporter KCC2 (Homo sapiens (Human))	BDBM44021 ((5Z)-3-(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyra...) Show SMILES Cc1c(N2C(=S)S\C(=C/c3ccc(C)cc3)C2=O)c(=O)n(-c2ccccc2)n1C Show InChI InChI=1S/C22H19N3O2S2/c1-14-9-11-16(12-10-14)13-18-20(26)24(22(28)29-18)19-15(2)23(3)25(21(19)27)17-7-5-4-6-8-17/h4-13H,1-3H3/b18-13-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Assay Provider: Eric Delpire Assay Provider Affliation: Vanderbilt University Gr...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2Q52N1X
					More data for this Ligand-Target Pair
Multidrug resistance protein 1/Multidrug resistance associated protein 1 (Homo sapiens (Human))	BDBM44021 ((5Z)-3-(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyra...) Show SMILES Cc1c(N2C(=S)S\C(=C/c3ccc(C)cc3)C2=O)c(=O)n(-c2ccccc2)n1C Show InChI InChI=1S/C22H19N3O2S2/c1-14-9-11-16(12-10-14)13-18-20(26)24(22(28)29-18)19-15(2)23(3)25(21(19)27)17-7-5-4-6-8-17/h4-13H,1-3H3/b18-13-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	5.23E+3	n/a	n/a	n/a	n/a
SRMLSC Curated by PubChem BioAssay					Assay Description Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...				PubChem Bioassay (2007) BindingDB Entry DOI: 10.7270/Q25719FH
					More data for this Ligand-Target Pair
Zinc aminopeptidase (Plasmodium falciparum (isolate FcB1 / Columbia))	BDBM44021 ((5Z)-3-(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyra...) Show SMILES Cc1c(N2C(=S)S\C(=C/c3ccc(C)cc3)C2=O)c(=O)n(-c2ccccc2)n1C Show InChI InChI=1S/C22H19N3O2S2/c1-14-9-11-16(12-10-14)13-18-20(26)24(22(28)29-18)19-15(2)23(3)25(21(19)27)17-7-5-4-6-8-17/h4-13H,1-3H3/b18-13-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
SRMLSC Curated by PubChem BioAssay					Assay Description Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q27H1H0J
					More data for this Ligand-Target Pair
electroneutral potassium-chloride cotransporter KCC2 (Homo sapiens (Human))	BDBM44021 ((5Z)-3-(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyra...) Show SMILES Cc1c(N2C(=S)S\C(=C/c3ccc(C)cc3)C2=O)c(=O)n(-c2ccccc2)n1C Show InChI InChI=1S/C22H19N3O2S2/c1-14-9-11-16(12-10-14)13-18-20(26)24(22(28)29-18)19-15(2)23(3)25(21(19)27)17-7-5-4-6-8-17/h4-13H,1-3H3/b18-13-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Assay Provider: Eric Delpire Assay Provider Affliation: Vanderbilt University Gr...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2M32T6M
					More data for this Ligand-Target Pair
electroneutral potassium-chloride cotransporter KCC2 (Homo sapiens (Human))	BDBM44021 ((5Z)-3-(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyra...) Show SMILES Cc1c(N2C(=S)S\C(=C/c3ccc(C)cc3)C2=O)c(=O)n(-c2ccccc2)n1C Show InChI InChI=1S/C22H19N3O2S2/c1-14-9-11-16(12-10-14)13-18-20(26)24(22(28)29-18)19-15(2)23(3)25(21(19)27)17-7-5-4-6-8-17/h4-13H,1-3H3/b18-13-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay					Assay Description Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Assay Provider: Eric Delpire Assay Provider Affliation: Vanderbilt University Gr...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2TX3CSC
					More data for this Ligand-Target Pair