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SMILES: CCn1nc(-c2ccccc2)c2nc3ccccc3nc12

InChI Key: InChIKey=WKXGDKXWDPBUFH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 44437   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-A receptor 4 (Mus musculus)	BDBM44437 (1-ethyl-3-phenyl-pyrazolo[4,3-b]quinoxaline | 1-et...) Show SMILES CCn1nc(-c2ccccc2)c2nc3ccccc3nc12 Show InChI InChI=1S/C17H14N4/c1-2-21-17-16(15(20-21)12-8-4-3-5-9-12)18-13-10-6-7-11-14(13)19-17/h3-11H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2P55KW4
					More data for this Ligand-Target Pair
Ephrin type-A receptor 4 (Mus musculus)	BDBM44437 (1-ethyl-3-phenyl-pyrazolo[4,3-b]quinoxaline | 1-et...) Show SMILES CCn1nc(-c2ccccc2)c2nc3ccccc3nc12 Show InChI InChI=1S/C17H14N4/c1-2-21-17-16(15(20-21)12-8-4-3-5-9-12)18-13-10-6-7-11-14(13)19-17/h3-11H,2H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2JD4V5T
					More data for this Ligand-Target Pair
Tropomyosin alpha-1 chain (Sus scrofa)	BDBM44437 (1-ethyl-3-phenyl-pyrazolo[4,3-b]quinoxaline | 1-et...) Show SMILES CCn1nc(-c2ccccc2)c2nc3ccccc3nc12 Show InChI InChI=1S/C17H14N4/c1-2-21-17-16(15(20-21)12-8-4-3-5-9-12)18-13-10-6-7-11-14(13)19-17/h3-11H,2H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	5.55E+3	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q21N7ZKB
					More data for this Ligand-Target Pair
Corticotropin-releasing factor-binding protein (Homo sapiens (Human))	BDBM44437 (1-ethyl-3-phenyl-pyrazolo[4,3-b]quinoxaline | 1-et...) Show SMILES CCn1nc(-c2ccccc2)c2nc3ccccc3nc12 Show InChI InChI=1S/C17H14N4/c1-2-21-17-16(15(20-21)12-8-4-3-5-9-12)18-13-10-6-7-11-14(13)19-17/h3-11H,2H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	6.66E+3	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2VX0F3D
					More data for this Ligand-Target Pair
Endoribonuclease toxin MazF (Escherichia coli str. K-12 substr. MG1655)	BDBM44437 (1-ethyl-3-phenyl-pyrazolo[4,3-b]quinoxaline | 1-et...) Show SMILES CCn1nc(-c2ccccc2)c2nc3ccccc3nc12 Show InChI InChI=1S/C17H14N4/c1-2-21-17-16(15(20-21)12-8-4-3-5-9-12)18-13-10-6-7-11-14(13)19-17/h3-11H,2H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	8.40E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2TB15DB
					More data for this Ligand-Target Pair
Toll-like receptor 9 (Homo sapiens (Human))	BDBM44437 (1-ethyl-3-phenyl-pyrazolo[4,3-b]quinoxaline | 1-et...) Show SMILES CCn1nc(-c2ccccc2)c2nc3ccccc3nc12 Show InChI InChI=1S/C17H14N4/c1-2-21-17-16(15(20-21)12-8-4-3-5-9-12)18-13-10-6-7-11-14(13)19-17/h3-11H,2H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	7.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2KS6Q2P
					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa)	BDBM44437 (1-ethyl-3-phenyl-pyrazolo[4,3-b]quinoxaline | 1-et...) Show SMILES CCn1nc(-c2ccccc2)c2nc3ccccc3nc12 Show InChI InChI=1S/C17H14N4/c1-2-21-17-16(15(20-21)12-8-4-3-5-9-12)18-13-10-6-7-11-14(13)19-17/h3-11H,2H2,1H3	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2G15ZB8
					More data for this Ligand-Target Pair
Endoribonuclease toxin MazF (Escherichia coli str. K-12 substr. MG1655)	BDBM44437 (1-ethyl-3-phenyl-pyrazolo[4,3-b]quinoxaline | 1-et...) Show SMILES CCn1nc(-c2ccccc2)c2nc3ccccc3nc12 Show InChI InChI=1S/C17H14N4/c1-2-21-17-16(15(20-21)12-8-4-3-5-9-12)18-13-10-6-7-11-14(13)19-17/h3-11H,2H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>9.90E+4	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2Z31X54
					More data for this Ligand-Target Pair