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BDBM46184 MLS-0202048.0001::N-[2,3-bis(2-furanyl)-6-quinoxalinyl]-4-morpholinecarboxamide::N-[2,3-bis(2-furyl)quinoxalin-6-yl]morpholine-4-carboxamide::N-[2,3-bis(furan-2-yl)quinoxalin-6-yl]morpholine-4-carboxamide::cid_1072900

SMILES: O=C(Nc1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1)N1CCOCC1

InChI Key: InChIKey=DFTFDBZTSJXMRZ-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 46184   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hematopoietic protein-tyrosine phosphatase (HEPTP)


(Homo sapiens (Human))
BDBM46184
PNG
(MLS-0202048.0001 | N-[2,3-bis(2-furanyl)-6-quinoxa...)
Show SMILES O=C(Nc1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1)N1CCOCC1
Show InChI InChI=1S/C21H18N4O4/c26-21(25-7-11-27-12-8-25)22-14-5-6-15-16(13-14)24-20(18-4-2-10-29-18)19(23-15)17-3-1-9-28-17/h1-6,9-10,13H,7-8,11-12H2,(H,22,26)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
PCBioAssay
n/an/a 1.61E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2474894
More data for this
Ligand-Target Pair
neuronal munc18-1 binding protein


(Rattus norvegicus)
BDBM46184
PNG
(MLS-0202048.0001 | N-[2,3-bis(2-furanyl)-6-quinoxa...)
Show SMILES O=C(Nc1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1)N1CCOCC1
Show InChI InChI=1S/C21H18N4O4/c26-21(25-7-11-27-12-8-25)22-14-5-6-15-16(13-14)24-20(18-4-2-10-29-18)19(23-15)17-3-1-9-28-17/h1-6,9-10,13H,7-8,11-12H2,(H,22,26)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PCBioAssay
n/an/a 2.23E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2010)


Article DOI: 10.1002/cbic.201300770
BindingDB Entry DOI: 10.7270/Q21V5CDC
More data for this
Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP)


(Homo sapiens (Human))
BDBM46184
PNG
(MLS-0202048.0001 | N-[2,3-bis(2-furanyl)-6-quinoxa...)
Show SMILES O=C(Nc1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1)N1CCOCC1
Show InChI InChI=1S/C21H18N4O4/c26-21(25-7-11-27-12-8-25)22-14-5-6-15-16(13-14)24-20(18-4-2-10-29-18)19(23-15)17-3-1-9-28-17/h1-6,9-10,13H,7-8,11-12H2,(H,22,26)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
PCBioAssay
n/an/a 693n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q21N7ZJW
More data for this
Ligand-Target Pair