BDBM46281 2-[4-[(Z)-[2-(4-fluoroanilino)-4-keto-2-thiazolin-5-ylidene]methyl]phenoxy]acetic acid methyl ester::2-[4-[(Z)-[2-(4-fluoroanilino)-4-oxo-5-thiazolylidene]methyl]phenoxy]acetic acid methyl ester::MLS-0425606.0001::cid_5766720::methyl 2-[4-[(Z)-[2-(4-fluoroanilino)-4-oxo-1,3-thiazol-5-ylidene]methyl]phenoxy]acetate::methyl 2-[4-[(Z)-[2-[(4-fluorophenyl)amino]-4-oxidanylidene-1,3-thiazol-5-ylidene]methyl]phenoxy]ethanoate

SMILES: COC(=O)COc1ccc(C=C2SC(Nc3ccc(F)cc3)=NC2=O)cc1

InChI Key: InChIKey=HIOCJJAPBFRSHV-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 46281   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM46281 (2-[4-[(Z)-[2-(4-fluoroanilino)-4-keto-2-thiazolin-...) Show SMILES COC(=O)COc1ccc(C=C2SC(Nc3ccc(F)cc3)=NC2=O)cc1 |w:10.9,c:22| Show InChI InChI=1S/C19H15FN2O4S/c1-25-17(23)11-26-15-8-2-12(3-9-15)10-16-18(24)22-19(27-16)21-14-6-4-13(20)5-7-14/h2-10H,11H2,1H3,(H,21,22,24)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2474894
					More data for this Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM46281 (2-[4-[(Z)-[2-(4-fluoroanilino)-4-keto-2-thiazolin-...) Show SMILES COC(=O)COc1ccc(C=C2SC(Nc3ccc(F)cc3)=NC2=O)cc1 |w:10.9,c:22| Show InChI InChI=1S/C19H15FN2O4S/c1-25-17(23)11-26-15-8-2-12(3-9-15)10-16-18(24)22-19(27-16)21-14-6-4-13(20)5-7-14/h2-10H,11H2,1H3,(H,21,22,24)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q21N7ZJW
					More data for this Ligand-Target Pair
tyrosine-protein phosphatase non-receptor type 12 isoform 2 (Homo sapiens (Human))	BDBM46281 (2-[4-[(Z)-[2-(4-fluoroanilino)-4-keto-2-thiazolin-...) Show SMILES COC(=O)COc1ccc(C=C2SC(Nc3ccc(F)cc3)=NC2=O)cc1 |w:10.9,c:22| Show InChI InChI=1S/C19H15FN2O4S/c1-25-17(23)11-26-15-8-2-12(3-9-15)10-16-18(24)22-19(27-16)21-14-6-4-13(20)5-7-14/h2-10H,11H2,1H3,(H,21,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	975	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q28G8J5T
					More data for this Ligand-Target Pair
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM46281 (2-[4-[(Z)-[2-(4-fluoroanilino)-4-keto-2-thiazolin-...) Show SMILES COC(=O)COc1ccc(C=C2SC(Nc3ccc(F)cc3)=NC2=O)cc1 |w:10.9,c:22| Show InChI InChI=1S/C19H15FN2O4S/c1-25-17(23)11-26-15-8-2-12(3-9-15)10-16-18(24)22-19(27-16)21-14-6-4-13(20)5-7-14/h2-10H,11H2,1H3,(H,21,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2M9073J
					More data for this Ligand-Target Pair
Hematopoietic protein-tyrosine phosphatase (HEPTP) (Homo sapiens (Human))	BDBM46281 (2-[4-[(Z)-[2-(4-fluoroanilino)-4-keto-2-thiazolin-...) Show SMILES COC(=O)COc1ccc(C=C2SC(Nc3ccc(F)cc3)=NC2=O)cc1 |w:10.9,c:22| Show InChI InChI=1S/C19H15FN2O4S/c1-25-17(23)11-26-15-8-2-12(3-9-15)10-16-18(24)22-19(27-16)21-14-6-4-13(20)5-7-14/h2-10H,11H2,1H3,(H,21,22,24)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2BR8QNJ
					More data for this Ligand-Target Pair
Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP (Homo sapiens (Human))	BDBM46281 (2-[4-[(Z)-[2-(4-fluoroanilino)-4-keto-2-thiazolin-...) Show SMILES COC(=O)COc1ccc(C=C2SC(Nc3ccc(F)cc3)=NC2=O)cc1 |w:10.9,c:22| Show InChI InChI=1S/C19H15FN2O4S/c1-25-17(23)11-26-15-8-2-12(3-9-15)10-16-18(24)22-19(27-16)21-14-6-4-13(20)5-7-14/h2-10H,11H2,1H3,(H,21,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2QZ28FP
					More data for this Ligand-Target Pair