BDBM46388 3-(4-fluorobenzyl)oxy-2-methyl-quinoline::3-[(4-fluorobenzyl)oxy]-2-methylquinoline::3-[(4-fluorophenyl)methoxy]-2-methyl-quinoline::3-[(4-fluorophenyl)methoxy]-2-methylquinoline::MLS000547371::SMR000180270::cid_3787931

SMILES: Cc1nc2ccccc2cc1OCc1ccc(F)cc1

InChI Key: InChIKey=UCKMAYAEGOOXBZ-UHFFFAOYSA-N

Data: 4 IC50  3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 46388   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
STAT3 (Homo sapiens (Human))	BDBM46388 (3-(4-fluorobenzyl)oxy-2-methyl-quinoline | 3-[(4-f...) Show SMILES Cc1nc2ccccc2cc1OCc1ccc(F)cc1 Show InChI InChI=1S/C17H14FNO/c1-12-17(10-14-4-2-3-5-16(14)19-12)20-11-13-6-8-15(18)9-7-13/h2-10H,11H2,1H3	GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2TQ5ZXW
					More data for this Ligand-Target Pair
Transcription Factor STAT1 (Homo sapiens (Human))	BDBM46388 (3-(4-fluorobenzyl)oxy-2-methyl-quinoline | 3-[(4-f...) Show SMILES Cc1nc2ccccc2cc1OCc1ccc(F)cc1 Show InChI InChI=1S/C17H14FNO/c1-12-17(10-14-4-2-3-5-16(14)19-12)20-11-13-6-8-15(18)9-7-13/h2-10H,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>5.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2K935ZR
					More data for this Ligand-Target Pair
heat shock protein 90 (Candida albicans)	BDBM46388 (3-(4-fluorobenzyl)oxy-2-methyl-quinoline | 3-[(4-f...) Show SMILES Cc1nc2ccccc2cc1OCc1ccc(F)cc1 Show InChI InChI=1S/C17H14FNO/c1-12-17(10-14-4-2-3-5-16(14)19-12)20-11-13-6-8-15(18)9-7-13/h2-10H,11H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	7.27E+3	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Broad Institute: Reversing Antifungal Drug Resistance Project ID: 2037 Keywords: Candida albicans, drug resistance, fluconazole, Hsp90, Calcineurin, ...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2MC8XGG
					More data for this Ligand-Target Pair
Protein HSP-16.2 (Caenorhabditis elegans)	BDBM46388 (3-(4-fluorobenzyl)oxy-2-methyl-quinoline | 3-[(4-f...) Show SMILES Cc1nc2ccccc2cc1OCc1ccc(F)cc1 Show InChI InChI=1S/C17H14FNO/c1-12-17(10-14-4-2-3-5-16(14)19-12)20-11-13-6-8-15(18)9-7-13/h2-10H,11H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>6.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q21J98BN
					More data for this Ligand-Target Pair
calcineurin A1, putative (Candida dubliniensis CD36)	BDBM46388 (3-(4-fluorobenzyl)oxy-2-methyl-quinoline | 3-[(4-f...) Show SMILES Cc1nc2ccccc2cc1OCc1ccc(F)cc1 Show InChI InChI=1S/C17H14FNO/c1-12-17(10-14-4-2-3-5-16(14)19-12)20-11-13-6-8-15(18)9-7-13/h2-10H,11H2,1H3	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>2.85E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Candida albicans, drug resistance, Fluconazole, calcineurin, stress response Assay Overview: Method for determining if compound acts as Ca...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2ZP44K0
					More data for this Ligand-Target Pair
SKiNhead family member (skn-1) (Caenorhabditis elegans)	BDBM46388 (3-(4-fluorobenzyl)oxy-2-methyl-quinoline | 3-[(4-f...) Show SMILES Cc1nc2ccccc2cc1OCc1ccc(F)cc1 Show InChI InChI=1S/C17H14FNO/c1-12-17(10-14-4-2-3-5-16(14)19-12)20-11-13-6-8-15(18)9-7-13/h2-10H,11H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay									PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2DV1HH8
					More data for this Ligand-Target Pair
heat shock protein 90 (Candida albicans)	BDBM46388 (3-(4-fluorobenzyl)oxy-2-methyl-quinoline | 3-[(4-f...) Show SMILES Cc1nc2ccccc2cc1OCc1ccc(F)cc1 Show InChI InChI=1S/C17H14FNO/c1-12-17(10-14-4-2-3-5-16(14)19-12)20-11-13-6-8-15(18)9-7-13/h2-10H,11H2,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	4.69E+4	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, stress response Assay Overview: Method for determining if compound acts as Hsp90 inh...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2GM85R4
					More data for this Ligand-Target Pair