BDBM4734 5-Acetylamino-6-[(aminoiminomethyl)amino]pyridine-2-carboxylic acid::6-carbamimidamido-5-acetamidopyridine-2-carboxylic acid::pyridine deriv. 35

SMILES: CC(=O)Nc1ccc(nc1N=C(N)N)C(O)=O

InChI Key: InChIKey=GHPBFMJFCNOSSO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4734   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuraminidase A (Influenza A virus (N9))	BDBM4734 (5-Acetylamino-6-[(aminoiminomethyl)amino]pyridine-...) Show SMILES CC(=O)Nc1ccc(nc1N=C(N)N)C(O)=O |w:10.10| Show InChI InChI=1S/C9H11N5O3/c1-4(15)12-5-2-3-6(8(16)17)13-7(5)14-9(10)11/h2-3H,1H3,(H,12,15)(H,16,17)(H4,10,11,13,14)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	6.5	37
BioCryst Pharmaceuticals, Inc.					Assay Description A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...				Bioorg Med Chem 13: 2665-78 (2005) Article DOI: 10.1016/j.bmc.2005.01.042 BindingDB Entry DOI: 10.7270/Q2SF2TD9
					More data for this Ligand-Target Pair