BDBM47468 MLS000769840::N-(2-phenylethyl)-2-(2-pyridinyl)-4-quinazolinamine::N-(2-phenylethyl)-2-pyridin-2-yl-quinazolin-4-amine::N-(2-phenylethyl)-2-pyridin-2-ylquinazolin-4-amine::Phenethyl-(2-pyridin-2-yl-quinazolin-4-yl)-amine::SMR000434573::cid_937982::phenethyl-[2-(2-pyridyl)quinazolin-4-yl]amine
SMILES: C(Cc1ccccc1)Nc1nc(nc2ccccc12)-c1ccccn1
InChI Key: InChIKey=FIBATSPGNRZQTN-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM47468 (MLS000769840 | N-(2-phenylethyl)-2-(2-pyridinyl)-4...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 3.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q20863Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM47468 (MLS000769840 | N-(2-phenylethyl)-2-(2-pyridinyl)-4...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 6.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2QN656Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM47468 (MLS000769840 | N-(2-phenylethyl)-2-(2-pyridinyl)-4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Inhibition of human methionine aminopeptidase 2 in presence of Mn2+ | J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methionine Aminopeptidase Type 1 (MetAP1) (Homo sapiens (Human)) | BDBM47468 (MLS000769840 | N-(2-phenylethyl)-2-(2-pyridinyl)-4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 940 | n/a | n/a | n/a | n/a |
Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Co2+ | J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Methionine Aminopeptidase Type 1 (MetAP1) (Homo sapiens (Human)) | BDBM47468 (MLS000769840 | N-(2-phenylethyl)-2-(2-pyridinyl)-4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a |
Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Inhibition of human methionine aminopeptidase 1 in presence of Mn2+ | J Med Chem 56: 3996-4016 (2013) Article DOI: 10.1021/jm400227z BindingDB Entry DOI: 10.7270/Q2SJ1N1Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
BZLF1 (Human herpesvirus 4) | BDBM47468 (MLS000769840 | N-(2-phenylethyl)-2-(2-pyridinyl)-4...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 4.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2BC3X0T | |||||||||||
More data for this Ligand-Target Pair |