BDBM47658 1-(4-methylphenyl)-3-(2-pyridin-3-ylpyrimidin-4-yl)urea::1-(4-methylphenyl)-3-[2-(3-pyridinyl)-4-pyrimidinyl]urea::1-(p-tolyl)-3-[2-(3-pyridyl)pyrimidin-4-yl]urea::MLS000706883::N-(4-methylphenyl)-N'-[2-(3-pyridinyl)-4-pyrimidinyl]urea::SMR000335712::cid_1477566

SMILES: Cc1ccc(NC(=O)Nc2ccnc(n2)-c2cccnc2)cc1

InChI Key: InChIKey=FCFZSPVQFIPQML-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 47658   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cdc2-related kinase (Leishmania major)	BDBM47658 (1-(4-methylphenyl)-3-(2-pyridin-3-ylpyrimidin-4-yl...) Show SMILES Cc1ccc(NC(=O)Nc2ccnc(n2)-c2cccnc2)cc1 Show InChI InChI=1S/C17H15N5O/c1-12-4-6-14(7-5-12)20-17(23)22-15-8-10-19-16(21-15)13-3-2-9-18-11-13/h2-11H,1H3,(H2,19,20,21,22,23)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Montclair State University Curated by ChEMBL					Assay Description Inhibition of Leishmania major CRK3 expressed in Escherichia coli BL21 (DE3) using 5FAM-GGGRSPGRRRRK-OH as substrate after 60 mins by IMAP assay				Bioorg Med Chem Lett 22: 6788-93 (2012) Article DOI: 10.1016/j.bmcl.2012.09.044 BindingDB Entry DOI: 10.7270/Q26H4JJZ
					More data for this Ligand-Target Pair
glutathione S-transferase (Homo sapiens (Human))	BDBM47658 (1-(4-methylphenyl)-3-(2-pyridin-3-ylpyrimidin-4-yl...) Show SMILES Cc1ccc(NC(=O)Nc2ccnc(n2)-c2cccnc2)cc1 Show InChI InChI=1S/C17H15N5O/c1-12-4-6-14(7-5-12)20-17(23)22-15-8-10-19-16(21-15)13-3-2-9-18-11-13/h2-11H,1H3,(H2,19,20,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	2.07E+3	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-re...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2ZC8184
					More data for this Ligand-Target Pair