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BDBM47714 (2Z)-3-ethyl-2-[(2E,4E)-5-(3-ethyl-1,3-benzothiazol-3-ium-2-yl)penta-2,4-dienylidene]-1,3-benzothiazole;iodide::3,3'-DIETHYLTHIADICARBOCYANINE IODIDE::Dithiazanine::MLS000069807::SMR000059184::cid_5702697
SMILES: CCN1\C(Sc2ccccc12)=C\C=C\C=C\c1sc2ccccc2[n+]1CC
InChI Key: InChIKey=FYXWDSGGZAMYFZ-UHFFFAOYSA-N
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| RGS7 (Homo sapiens (Human)) | BDBM47714 ((2Z)-3-ethyl-2-[(2E,4E)-5-(3-ethyl-1,3-benzothiazo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet  | KEGG PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a |
NMMLSC Curated by PubChem BioAssay | Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2PV6HS7 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| G protein signalling regulator 19 (Homo sapiens (Human)) | BDBM47714 ((2Z)-3-ethyl-2-[(2E,4E)-5-(3-ethyl-1,3-benzothiazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a |
NMMLSC Curated by PubChem BioAssay | Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2K35S27 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| regulator of G-protein signalling 16 (Homo sapiens (Human)) | BDBM47714 ((2Z)-3-ethyl-2-[(2E,4E)-5-(3-ethyl-1,3-benzothiazo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 6.67E+3 | n/a | n/a | n/a | n/a |
NMMLSC Curated by PubChem BioAssay | Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2FB51BW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Regulator of G-protein signaling 8 (Homo sapiens (Human)) | BDBM47714 ((2Z)-3-ethyl-2-[(2E,4E)-5-(3-ethyl-1,3-benzothiazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 5.69E+3 | n/a | n/a | n/a | n/a |
NMMLSC Curated by PubChem BioAssay | Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2TM78JD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| DNA damage-inducible transcript 3 protein (Mus musculus) | BDBM47714 ((2Z)-3-ethyl-2-[(2E,4E)-5-(3-ethyl-1,3-benzothiazo...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay | Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... | PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q28C9TQN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| DNA damage-inducible transcript 3 protein (Mus musculus) | BDBM47714 ((2Z)-3-ethyl-2-[(2E,4E)-5-(3-ethyl-1,3-benzothiazo...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay | Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2PC30VZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| NACHT, LRR and PYD domains-containing protein 1 isoform 1 (Homo sapiens (Human)) | BDBM47714 ((2Z)-3-ethyl-2-[(2E,4E)-5-(3-ethyl-1,3-benzothiazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 1.95E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q22Z140X | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Caspase-1 (Homo sapiens (Human)) | BDBM47714 ((2Z)-3-ethyl-2-[(2E,4E)-5-(3-ethyl-1,3-benzothiazo...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2TD9VTQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| XBP1 (Homo sapiens (Human)) | BDBM47714 ((2Z)-3-ethyl-2-[(2E,4E)-5-(3-ethyl-1,3-benzothiazo...) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 2.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay | Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... | PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2NK3CGB | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| regulator of G-protein signaling 4 (Homo sapiens (Human)) | BDBM47714 ((2Z)-3-ethyl-2-[(2E,4E)-5-(3-ethyl-1,3-benzothiazo...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 3.41E+3 | n/a | n/a | n/a | n/a |
NMMLSC Curated by PubChem BioAssay | Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2F76B0G | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
