BDBM47747 4-[(E)-[3-[3-(diethylsulfamoyl)phenyl]-5-thioxo-1H-1,2,4-triazol-4-yl]iminomethyl]benzoic acid methyl ester::4-[[3-[3-(diethylsulfamoyl)phenyl]-5-sulfanylidene-1H-1,2,4-triazol-4-yl]iminomethyl]benzoic acid methyl ester::4-[[3-[3-(diethylsulfamoyl)phenyl]-5-thioxo-1H-1,2,4-triazol-4-yl]iminomethyl]benzoic acid methyl ester::MLS000408811::SMR000243078::cid_2387418::methyl 4-[[3-[3-(diethylsulfamoyl)phenyl]-5-sulfanylidene-1H-1,2,4-triazol-4-yl]iminomethyl]benzoate

SMILES: CCN(CC)S(=O)(=O)c1cccc(c1)-c1n[nH]c(=S)n1N=Cc1ccc(cc1)C(=O)OC

InChI Key: InChIKey=YVOXJUJCHARNBE-UHFFFAOYSA-N

Data: 3 KI  10 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 47747   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
regulator of G-protein signalling 16 (Homo sapiens (Human))	BDBM47747 (4-[(E)-[3-[3-(diethylsulfamoyl)phenyl]-5-thioxo-1H...) Show SMILES CCN(CC)S(=O)(=O)c1cccc(c1)-c1n[nH]c(=S)n1N=Cc1ccc(cc1)C(=O)OC |w:20.21| Show InChI InChI=1S/C21H23N5O4S2/c1-4-25(5-2)32(28,29)18-8-6-7-17(13-18)19-23-24-21(31)26(19)22-14-15-9-11-16(12-10-15)20(27)30-3/h6-14H,4-5H2,1-3H3,(H,24,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2QR4VJR
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 8 (Homo sapiens (Human))	BDBM47747 (4-[(E)-[3-[3-(diethylsulfamoyl)phenyl]-5-thioxo-1H...) Show SMILES CCN(CC)S(=O)(=O)c1cccc(c1)-c1n[nH]c(=S)n1N=Cc1ccc(cc1)C(=O)OC |w:20.21| Show InChI InChI=1S/C21H23N5O4S2/c1-4-25(5-2)32(28,29)18-8-6-7-17(13-18)19-23-24-21(31)26(19)22-14-15-9-11-16(12-10-15)20(27)30-3/h6-14H,4-5H2,1-3H3,(H,24,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	2.59E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2G73C4V
					More data for this Ligand-Target Pair
regulator of G-protein signaling 4 (Homo sapiens (Human))	BDBM47747 (4-[(E)-[3-[3-(diethylsulfamoyl)phenyl]-5-thioxo-1H...) Show SMILES CCN(CC)S(=O)(=O)c1cccc(c1)-c1n[nH]c(=S)n1N=Cc1ccc(cc1)C(=O)OC |w:20.21| Show InChI InChI=1S/C21H23N5O4S2/c1-4-25(5-2)32(28,29)18-8-6-7-17(13-18)19-23-24-21(31)26(19)22-14-15-9-11-16(12-10-15)20(27)30-3/h6-14H,4-5H2,1-3H3,(H,24,31)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q27P8WVP
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 8 (Homo sapiens (Human))	BDBM47747 (4-[(E)-[3-[3-(diethylsulfamoyl)phenyl]-5-thioxo-1H...) Show SMILES CCN(CC)S(=O)(=O)c1cccc(c1)-c1n[nH]c(=S)n1N=Cc1ccc(cc1)C(=O)OC |w:20.21| Show InChI InChI=1S/C21H23N5O4S2/c1-4-25(5-2)32(28,29)18-8-6-7-17(13-18)19-23-24-21(31)26(19)22-14-15-9-11-16(12-10-15)20(27)30-3/h6-14H,4-5H2,1-3H3,(H,24,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2TM78JD
					More data for this Ligand-Target Pair
regulator of G-protein signaling 4 (Homo sapiens (Human))	BDBM47747 (4-[(E)-[3-[3-(diethylsulfamoyl)phenyl]-5-thioxo-1H...) Show SMILES CCN(CC)S(=O)(=O)c1cccc(c1)-c1n[nH]c(=S)n1N=Cc1ccc(cc1)C(=O)OC |w:20.21| Show InChI InChI=1S/C21H23N5O4S2/c1-4-25(5-2)32(28,29)18-8-6-7-17(13-18)19-23-24-21(31)26(19)22-14-15-9-11-16(12-10-15)20(27)30-3/h6-14H,4-5H2,1-3H3,(H,24,31)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2F76B0G
					More data for this Ligand-Target Pair
regulator of G-protein signaling 4 (Homo sapiens (Human))	BDBM47747 (4-[(E)-[3-[3-(diethylsulfamoyl)phenyl]-5-thioxo-1H...) Show SMILES CCN(CC)S(=O)(=O)c1cccc(c1)-c1n[nH]c(=S)n1N=Cc1ccc(cc1)C(=O)OC |w:20.21| Show InChI InChI=1S/C21H23N5O4S2/c1-4-25(5-2)32(28,29)18-8-6-7-17(13-18)19-23-24-21(31)26(19)22-14-15-9-11-16(12-10-15)20(27)30-3/h6-14H,4-5H2,1-3H3,(H,24,31)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	9.64E+3	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2CF9NJZ
					More data for this Ligand-Target Pair
G protein signalling regulator 19 (Homo sapiens (Human))	BDBM47747 (4-[(E)-[3-[3-(diethylsulfamoyl)phenyl]-5-thioxo-1H...) Show SMILES CCN(CC)S(=O)(=O)c1cccc(c1)-c1n[nH]c(=S)n1N=Cc1ccc(cc1)C(=O)OC |w:20.21| Show InChI InChI=1S/C21H23N5O4S2/c1-4-25(5-2)32(28,29)18-8-6-7-17(13-18)19-23-24-21(31)26(19)22-14-15-9-11-16(12-10-15)20(27)30-3/h6-14H,4-5H2,1-3H3,(H,24,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2BG2MFK
					More data for this Ligand-Target Pair
regulator of G-protein signalling 16 (Homo sapiens (Human))	BDBM47747 (4-[(E)-[3-[3-(diethylsulfamoyl)phenyl]-5-thioxo-1H...) Show SMILES CCN(CC)S(=O)(=O)c1cccc(c1)-c1n[nH]c(=S)n1N=Cc1ccc(cc1)C(=O)OC |w:20.21| Show InChI InChI=1S/C21H23N5O4S2/c1-4-25(5-2)32(28,29)18-8-6-7-17(13-18)19-23-24-21(31)26(19)22-14-15-9-11-16(12-10-15)20(27)30-3/h6-14H,4-5H2,1-3H3,(H,24,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2FB51BW
					More data for this Ligand-Target Pair
regulator of G-protein signalling 16 (Homo sapiens (Human))	BDBM47747 (4-[(E)-[3-[3-(diethylsulfamoyl)phenyl]-5-thioxo-1H...) Show SMILES CCN(CC)S(=O)(=O)c1cccc(c1)-c1n[nH]c(=S)n1N=Cc1ccc(cc1)C(=O)OC |w:20.21| Show InChI InChI=1S/C21H23N5O4S2/c1-4-25(5-2)32(28,29)18-8-6-7-17(13-18)19-23-24-21(31)26(19)22-14-15-9-11-16(12-10-15)20(27)30-3/h6-14H,4-5H2,1-3H3,(H,24,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	940	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2VH5M8G
					More data for this Ligand-Target Pair
G protein signalling regulator 19 (Homo sapiens (Human))	BDBM47747 (4-[(E)-[3-[3-(diethylsulfamoyl)phenyl]-5-thioxo-1H...) Show SMILES CCN(CC)S(=O)(=O)c1cccc(c1)-c1n[nH]c(=S)n1N=Cc1ccc(cc1)C(=O)OC |w:20.21| Show InChI InChI=1S/C21H23N5O4S2/c1-4-25(5-2)32(28,29)18-8-6-7-17(13-18)19-23-24-21(31)26(19)22-14-15-9-11-16(12-10-15)20(27)30-3/h6-14H,4-5H2,1-3H3,(H,24,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	6.21E+3	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2K35S27
					More data for this Ligand-Target Pair
Regulator of G-protein signaling 8 (Homo sapiens (Human))	BDBM47747 (4-[(E)-[3-[3-(diethylsulfamoyl)phenyl]-5-thioxo-1H...) Show SMILES CCN(CC)S(=O)(=O)c1cccc(c1)-c1n[nH]c(=S)n1N=Cc1ccc(cc1)C(=O)OC |w:20.21| Show InChI InChI=1S/C21H23N5O4S2/c1-4-25(5-2)32(28,29)18-8-6-7-17(13-18)19-23-24-21(31)26(19)22-14-15-9-11-16(12-10-15)20(27)30-3/h6-14H,4-5H2,1-3H3,(H,24,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.13E+3	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2M043TQ
					More data for this Ligand-Target Pair
RGS7 (Homo sapiens (Human))	BDBM47747 (4-[(E)-[3-[3-(diethylsulfamoyl)phenyl]-5-thioxo-1H...) Show SMILES CCN(CC)S(=O)(=O)c1cccc(c1)-c1n[nH]c(=S)n1N=Cc1ccc(cc1)C(=O)OC |w:20.21| Show InChI InChI=1S/C21H23N5O4S2/c1-4-25(5-2)32(28,29)18-8-6-7-17(13-18)19-23-24-21(31)26(19)22-14-15-9-11-16(12-10-15)20(27)30-3/h6-14H,4-5H2,1-3H3,(H,24,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2PV6HS7
					More data for this Ligand-Target Pair
RGS7 (Homo sapiens (Human))	BDBM47747 (4-[(E)-[3-[3-(diethylsulfamoyl)phenyl]-5-thioxo-1H...) Show SMILES CCN(CC)S(=O)(=O)c1cccc(c1)-c1n[nH]c(=S)n1N=Cc1ccc(cc1)C(=O)OC |w:20.21| Show InChI InChI=1S/C21H23N5O4S2/c1-4-25(5-2)32(28,29)18-8-6-7-17(13-18)19-23-24-21(31)26(19)22-14-15-9-11-16(12-10-15)20(27)30-3/h6-14H,4-5H2,1-3H3,(H,24,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2416VG3
					More data for this Ligand-Target Pair