BDBM47816 6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid (3-methoxy-propyl)-amide::MLS001029502::SMR000425486::cid_3729555

SMILES: COCCCNC(=O)c1ccc2C(=O)c3ccccc3-c3onc1c23

InChI Key: InChIKey=LXUKGKQDBOPMHC-UHFFFAOYSA-N

Data: 4 IC50  6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 47816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Regulator of G-protein signaling 8 (Homo sapiens (Human))	BDBM47816 (6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid...) Show SMILES COCCCNC(=O)c1ccc2C(=O)c3ccccc3-c3onc1c23 Show InChI InChI=1S/C19H16N2O4/c1-24-10-4-9-20-19(23)14-8-7-13-15-16(14)21-25-18(15)12-6-3-2-5-11(12)17(13)22/h2-3,5-8H,4,9-10H2,1H3,(H,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	4.25E+3	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2TM78JD
					More data for this Ligand-Target Pair
RGS7 (Homo sapiens (Human))	BDBM47816 (6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid...) Show SMILES COCCCNC(=O)c1ccc2C(=O)c3ccccc3-c3onc1c23 Show InChI InChI=1S/C19H16N2O4/c1-24-10-4-9-20-19(23)14-8-7-13-15-16(14)21-25-18(15)12-6-3-2-5-11(12)17(13)22/h2-3,5-8H,4,9-10H2,1H3,(H,20,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2PV6HS7
					More data for this Ligand-Target Pair
G protein signalling regulator 19 (Homo sapiens (Human))	BDBM47816 (6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid...) Show SMILES COCCCNC(=O)c1ccc2C(=O)c3ccccc3-c3onc1c23 Show InChI InChI=1S/C19H16N2O4/c1-24-10-4-9-20-19(23)14-8-7-13-15-16(14)21-25-18(15)12-6-3-2-5-11(12)17(13)22/h2-3,5-8H,4,9-10H2,1H3,(H,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.87E+3	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2K35S27
					More data for this Ligand-Target Pair
regulator of G-protein signalling 16 (Homo sapiens (Human))	BDBM47816 (6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid...) Show SMILES COCCCNC(=O)c1ccc2C(=O)c3ccccc3-c3onc1c23 Show InChI InChI=1S/C19H16N2O4/c1-24-10-4-9-20-19(23)14-8-7-13-15-16(14)21-25-18(15)12-6-3-2-5-11(12)17(13)22/h2-3,5-8H,4,9-10H2,1H3,(H,20,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	5.69E+3	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2FB51BW
					More data for this Ligand-Target Pair
Apoptotic peptidase activating factor 1 (Homo sapiens (Human))	BDBM47816 (6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid...) Show SMILES COCCCNC(=O)c1ccc2C(=O)c3ccccc3-c3onc1c23 Show InChI InChI=1S/C19H16N2O4/c1-24-10-4-9-20-19(23)14-8-7-13-15-16(14)21-25-18(15)12-6-3-2-5-11(12)17(13)22/h2-3,5-8H,4,9-10H2,1H3,(H,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2F18X8S
					More data for this Ligand-Target Pair
regulator of G-protein signaling 4 (Homo sapiens (Human))	BDBM47816 (6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid...) Show SMILES COCCCNC(=O)c1ccc2C(=O)c3ccccc3-c3onc1c23 Show InChI InChI=1S/C19H16N2O4/c1-24-10-4-9-20-19(23)14-8-7-13-15-16(14)21-25-18(15)12-6-3-2-5-11(12)17(13)22/h2-3,5-8H,4,9-10H2,1H3,(H,20,23)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.08E+3	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH R21NS057014 HTS to identify small molecule regulators of RGS family protein interaction...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2F76B0G
					More data for this Ligand-Target Pair
Hsf1 protein (Mus musculus)	BDBM47816 (6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid...) Show SMILES COCCCNC(=O)c1ccc2C(=O)c3ccccc3-c3onc1c23 Show InChI InChI=1S/C19H16N2O4/c1-24-10-4-9-20-19(23)14-8-7-13-15-16(14)21-25-18(15)12-6-3-2-5-11(12)17(13)22/h2-3,5-8H,4,9-10H2,1H3,(H,20,23)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.48E+3	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2P55KXK
					More data for this Ligand-Target Pair
Caspase-9 (Homo sapiens (Human))	BDBM47816 (6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid...) Show SMILES COCCCNC(=O)c1ccc2C(=O)c3ccccc3-c3onc1c23 Show InChI InChI=1S/C19H16N2O4/c1-24-10-4-9-20-19(23)14-8-7-13-15-16(14)21-25-18(15)12-6-3-2-5-11(12)17(13)22/h2-3,5-8H,4,9-10H2,1H3,(H,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q25M647F
					More data for this Ligand-Target Pair
Apoptotic peptidase activating factor 1 (Homo sapiens (Human))	BDBM47816 (6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid...) Show SMILES COCCCNC(=O)c1ccc2C(=O)c3ccccc3-c3onc1c23 Show InChI InChI=1S/C19H16N2O4/c1-24-10-4-9-20-19(23)14-8-7-13-15-16(14)21-25-18(15)12-6-3-2-5-11(12)17(13)22/h2-3,5-8H,4,9-10H2,1H3,(H,20,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBIMR, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2JS9NZB
					More data for this Ligand-Target Pair
BZLF2 (Human herpesvirus 4 type 2)	BDBM47816 (6-Oxo-6H-anthra[1,9-cd]isoxazole-3-carboxylic acid...) Show SMILES COCCCNC(=O)c1ccc2C(=O)c3ccccc3-c3onc1c23 Show InChI InChI=1S/C19H16N2O4/c1-24-10-4-9-20-19(23)14-8-7-13-15-16(14)21-25-18(15)12-6-3-2-5-11(12)17(13)22/h2-3,5-8H,4,9-10H2,1H3,(H,20,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...				PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q2057DCW
					More data for this Ligand-Target Pair