BDBM47911 2-chloranyl-1-[(3Z)-3-indol-3-ylidene-5-(4-methoxyphenyl)-4-oxidanyl-pyrazolidin-1-yl]ethanone::2-chloro-1-[(3Z)-4-hydroxy-3-(3-indolylidene)-5-(4-methoxyphenyl)-1-pyrazolidinyl]ethanone::2-chloro-1-[(3Z)-4-hydroxy-3-indol-3-ylidene-5-(4-methoxyphenyl)pyrazolidin-1-yl]ethanone::MLS001172952::SMR000594709::cid_5859530
SMILES: COc1ccc(cc1)C1N(NC(C1=O)c1c[nH]c2ccccc12)C(=O)CCl
InChI Key: InChIKey=YUXRMQWZFVLLAB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bcl-2-like protein 11 (Homo sapiens (Human)) | BDBM47911 (2-chloranyl-1-[(3Z)-3-indol-3-ylidene-5-(4-methoxy...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | PCBioAssay | n/a | n/a | n/a | n/a | 6.83E+4 | n/a | n/a | n/a | n/a |
Broad Institute Curated by PubChem BioAssay | Assay Description Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q24J0CKJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3C-like protease (Avian infectious bronchitis virus) | BDBM47911 (2-chloranyl-1-[(3Z)-3-indol-3-ylidene-5-(4-methoxy...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | PCBioAssay | n/a | n/a | 3.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q29K48NM | |||||||||||
More data for this Ligand-Target Pair |