BDBM4858 1-(4-Chloroanilino)-4-[2-methylpyridin-4-ylmethyl]-phthalazine::CGP79787 Analog 43::N-(4-chlorophenyl)-4-[(2-methylpyridin-4-yl)methyl]phthalazin-1-amine

SMILES: Cc1cc(Cc2nnc(Nc3ccc(Cl)cc3)c3ccccc23)ccn1

InChI Key: InChIKey=ZQIINWWMLNWZKD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4858   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM4858 (1-(4-Chloroanilino)-4-[2-methylpyridin-4-ylmethyl]...) Show SMILES Cc1cc(Cc2nnc(Nc3ccc(Cl)cc3)c3ccccc23)ccn1 Show InChI InChI=1S/C21H17ClN4/c1-14-12-15(10-11-23-14)13-20-18-4-2-3-5-19(18)21(26-25-20)24-17-8-6-16(22)7-9-17/h2-12H,13H2,1H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharmaceuticals					Assay Description The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...				J Med Chem 43: 2310-23 (2000) Article DOI: 10.1021/jm9909443 BindingDB Entry DOI: 10.7270/Q24M92R5
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM4858 (1-(4-Chloroanilino)-4-[2-methylpyridin-4-ylmethyl]...) Show SMILES Cc1cc(Cc2nnc(Nc3ccc(Cl)cc3)c3ccccc23)ccn1 Show InChI InChI=1S/C21H17ClN4/c1-14-12-15(10-11-23-14)13-20-18-4-2-3-5-19(18)21(26-25-20)24-17-8-6-16(22)7-9-17/h2-12H,13H2,1H3,(H,24,26)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	7.5	22
Novartis Pharmaceuticals					Assay Description The in vitro kinase assays were performed in 96-well plates using the recombinant GST-fused kinase domains expressed in baculovirus and purified over...				J Med Chem 43: 2310-23 (2000) Article DOI: 10.1021/jm9909443 BindingDB Entry DOI: 10.7270/Q24M92R5
					More data for this Ligand-Target Pair