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BDBM48808 (5Z)-1-(2-furanylmethyl)-2-sulfanylidene-5-(thiophen-2-ylmethylidene)-1,3-diazinane-4,6-dione::(5Z)-1-(2-furfuryl)-5-(2-thenylidene)-2-thioxo-hexahydropyrimidine-4,6-quinone::(5Z)-1-(furan-2-ylmethyl)-2-sulfanylidene-5-(thiophen-2-ylmethylidene)-1,3-diazinane-4,6-dione::1-(2-furylmethyl)-5-(2-thienylmethylene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione::MLS000675728::SMR000292112::cid_2187432

SMILES: O=C1NC(=S)N(Cc2ccco2)C(=O)\C1=C/c1cccs1

InChI Key: InChIKey=WSGOCFLUKRWZNV-XFFZJAGNSA-N

Data: 1 IC50

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   Substructure
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 48808   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
eukaryotic translation initiation factor 4 gamma, 1 isoform 4


(Homo sapiens (Human))
BDBM48808
PNG
((5Z)-1-(2-furanylmethyl)-2-sulfanylidene-5-(thioph...)
Show SMILES O=C1NC(=S)N(Cc2ccco2)C(=O)\C1=C/c1cccs1
Show InChI InChI=1S/C14H10N2O3S2/c17-12-11(7-10-4-2-6-21-10)13(18)16(14(20)15-12)8-9-3-1-5-19-9/h1-7H,8H2,(H,15,17,20)/b11-7-
PDB

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PC cid
PC sid
UniChem
PCBioAssay
n/an/a 9.49E+3n/an/an/an/an/an/a



Emory University Molecular Libraries Screening Center

Curated by PubChem BioAssay


Assay Description
Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2RN3686
More data for this
Ligand-Target Pair