BDBM48816 MLS000334839::N-[5-[(4-cyanobenzyl)thio]-1,3,4-thiadiazol-2-yl]-1,3-benzothiazole-6-carboxamide::N-[5-[(4-cyanophenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]-1,3-benzothiazole-6-carboxamide::N-[5-[(4-cyanophenyl)methylthio]-1,3,4-thiadiazol-2-yl]-1,3-benzothiazole-6-carboxamide::SMR000249597::cid_2452051

SMILES: O=C(Nc1nnc(SCc2ccc(cc2)C#N)s1)c1ccc2ncsc2c1

InChI Key: InChIKey=HAHNOMZYNFFBHE-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 48816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
eukaryotic translation initiation factor 4 gamma, 1 isoform 4 (Homo sapiens (Human))	BDBM48816 (MLS000334839 | N-[5-[(4-cyanobenzyl)thio]-1,3,4-th...) Show SMILES O=C(Nc1nnc(SCc2ccc(cc2)C#N)s1)c1ccc2ncsc2c1 Show InChI InChI=1S/C18H11N5OS3/c19-8-11-1-3-12(4-2-11)9-25-18-23-22-17(27-18)21-16(24)13-5-6-14-15(7-13)26-10-20-14/h1-7,10H,9H2,(H,21,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay					Assay Description Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2RN3686
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM48816 (MLS000334839 | N-[5-[(4-cyanobenzyl)thio]-1,3,4-th...) Show SMILES O=C(Nc1nnc(SCc2ccc(cc2)C#N)s1)c1ccc2ncsc2c1 Show InChI InChI=1S/C18H11N5OS3/c19-8-11-1-3-12(4-2-11)9-25-18-23-22-17(27-18)21-16(24)13-5-6-14-15(7-13)26-10-20-14/h1-7,10H,9H2,(H,21,22,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	7.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2QN656Q
					More data for this Ligand-Target Pair
BZLF1 (Human herpesvirus 4)	BDBM48816 (MLS000334839 | N-[5-[(4-cyanobenzyl)thio]-1,3,4-th...) Show SMILES O=C(Nc1nnc(SCc2ccc(cc2)C#N)s1)c1ccc2ncsc2c1 Show InChI InChI=1S/C18H11N5OS3/c19-8-11-1-3-12(4-2-11)9-25-18-23-22-17(27-18)21-16(24)13-5-6-14-15(7-13)26-10-20-14/h1-7,10H,9H2,(H,21,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2BC3X0T
					More data for this Ligand-Target Pair
putative hexokinase HKDC1 (Homo sapiens (Human))	BDBM48816 (MLS000334839 | N-[5-[(4-cyanobenzyl)thio]-1,3,4-th...) Show SMILES O=C(Nc1nnc(SCc2ccc(cc2)C#N)s1)c1ccc2ncsc2c1 Show InChI InChI=1S/C18H11N5OS3/c19-8-11-1-3-12(4-2-11)9-25-18-23-22-17(27-18)21-16(24)13-5-6-14-15(7-13)26-10-20-14/h1-7,10H,9H2,(H,21,22,24)	GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q23F4N3R
					More data for this Ligand-Target Pair
photoreceptor-specific nuclear receptor (Homo sapiens (Human))	BDBM48816 (MLS000334839 | N-[5-[(4-cyanobenzyl)thio]-1,3,4-th...) Show SMILES O=C(Nc1nnc(SCc2ccc(cc2)C#N)s1)c1ccc2ncsc2c1 Show InChI InChI=1S/C18H11N5OS3/c19-8-11-1-3-12(4-2-11)9-25-18-23-22-17(27-18)21-16(24)13-5-6-14-15(7-13)26-10-20-14/h1-7,10H,9H2,(H,21,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2BK19S0
					More data for this Ligand-Target Pair
putative hexokinase HKDC1 (Homo sapiens (Human))	BDBM48816 (MLS000334839 | N-[5-[(4-cyanobenzyl)thio]-1,3,4-th...) Show SMILES O=C(Nc1nnc(SCc2ccc(cc2)C#N)s1)c1ccc2ncsc2c1 Show InChI InChI=1S/C18H11N5OS3/c19-8-11-1-3-12(4-2-11)9-25-18-23-22-17(27-18)21-16(24)13-5-6-14-15(7-13)26-10-20-14/h1-7,10H,9H2,(H,21,22,24)	GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2W094D4
					More data for this Ligand-Target Pair
nuclear receptor corepressor 2 isoform 2 (Homo sapiens (Human))	BDBM48816 (MLS000334839 | N-[5-[(4-cyanobenzyl)thio]-1,3,4-th...) Show SMILES O=C(Nc1nnc(SCc2ccc(cc2)C#N)s1)c1ccc2ncsc2c1 Show InChI InChI=1S/C18H11N5OS3/c19-8-11-1-3-12(4-2-11)9-25-18-23-22-17(27-18)21-16(24)13-5-6-14-15(7-13)26-10-20-14/h1-7,10H,9H2,(H,21,22,24)	PDB MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q26T0K34
					More data for this Ligand-Target Pair