BDBM49375 MLS000527505::N-(1,3-benzothiazol-2-yl)-2-phenyl-acetamide::N-(1,3-benzothiazol-2-yl)-2-phenyl-ethanamide::N-(1,3-benzothiazol-2-yl)-2-phenylacetamide::N-Benzothiazol-2-yl-2-phenyl-acetamide::SMR000117979::cid_591403
SMILES: O=C(Cc1ccccc1)Nc1nc2ccccc2s1
InChI Key: InChIKey=PJCPNGRABRSWOG-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nuclear factor NF-kappa-B (Homo sapiens (Human)) | BDBM49375 (MLS000527505 | N-(1,3-benzothiazol-2-yl)-2-phenyl-...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | n/a | 2.95E+4 | n/a | n/a | n/a | n/a |
SRMLSC Curated by PubChem BioAssay | Assay Description Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q27P8WT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Casein kinase I isoform delta (Homo sapiens (Human)) | BDBM49375 (MLS000527505 | N-(1,3-benzothiazol-2-yl)-2-phenyl-...) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
CSIC Curated by ChEMBL | Assay Description Inhibition of human recombinant CK-1delta using casein as substrate after 60 mins by Kinase-Glo assay | J Med Chem 57: 2755-72 (2014) Article DOI: 10.1021/jm500065f BindingDB Entry DOI: 10.7270/Q21N82NV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hsf1 protein (Mus musculus) | BDBM49375 (MLS000527505 | N-(1,3-benzothiazol-2-yl)-2-phenyl-...) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | n/a | >1.95E+5 | n/a | n/a | n/a | n/a |
Broad Institute Curated by PubChem BioAssay | Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2MW2FKX | |||||||||||
More data for this Ligand-Target Pair |