BDBM50000129 CHEMBL112763

SMILES: OC1C(O)C(NC(=O)c2ccc(F)c(F)c2)OC(C1O)C(O)=O

InChI Key: InChIKey=HYSCPTFKZDAZPL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000129   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor 2 (Homo sapiens (Human))	BDBM50000129 (CHEMBL112763) Show SMILES OC1C(O)C(NC(=O)c2ccc(F)c(F)c2)OC(C1O)C(O)=O Show InChI InChI=1S/C13H13F2NO7/c14-5-2-1-4(3-6(5)15)11(20)16-12-9(19)7(17)8(18)10(23-12)13(21)22/h1-3,7-10,12,17-19H,(H,16,20)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University College Dublin Curated by ChEMBL					Assay Description 25% inhibition of FGF-2 binding to heparin-albumin by ELISA				Bioorg Med Chem Lett 12: 3287-90 (2002) BindingDB Entry DOI: 10.7270/Q2ZP45G2
					More data for this Ligand-Target Pair