BDBM50000275 1-[2-(3,4-Dichloro-phenyl)-acetyl]-2-pyrrolidin-1-ylmethyl-piperidin-4-one::CHEMBL146884

SMILES: Clc1ccc(CC(=O)N2CCC(=O)CC2CN2CCCC2)cc1Cl

InChI Key: InChIKey=FACSGCXGQDFEDR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000275   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50000275 (1-[2-(3,4-Dichloro-phenyl)-acetyl]-2-pyrrolidin-1-...) Show SMILES Clc1ccc(CC(=O)N2CCC(=O)CC2CN2CCCC2)cc1Cl Show InChI InChI=1S/C18H22Cl2N2O2/c19-16-4-3-13(9-17(16)20)10-18(24)22-8-5-15(23)11-14(22)12-21-6-1-2-7-21/h3-4,9,14H,1-2,5-8,10-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Group Research Ltd. Curated by ChEMBL					Assay Description Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparation				J Med Chem 35: 490-501 (1992) BindingDB Entry DOI: 10.7270/Q2TQ60GV
					More data for this Ligand-Target Pair