BDBM50000315 (CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-pyridazin-3-one::6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-pyridazin-3-one::6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-pyridazin-3-one(CI-914)::6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-pyridazin-3-one(Imazodan)::CHEMBL12831::CI-914

SMILES: O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1

InChI Key: InChIKey=VXMYWVMXSWJFCV-UHFFFAOYSA-N

Data: 24 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50000315   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of cardiac phosphodiesterase-3 isolated from canine heart.				J Med Chem 33: 380-6 (1990) BindingDB Entry DOI: 10.7270/Q241708F
					More data for this Ligand-Target Pair
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of fraction III of guinea pig phosphodiesterase				J Med Chem 27: 1099-101 (1984) BindingDB Entry DOI: 10.7270/Q26Q1W70
					More data for this Ligand-Target Pair
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of fraction II of guinea pig phosphodiesterase				J Med Chem 27: 1099-101 (1984) BindingDB Entry DOI: 10.7270/Q26Q1W70
					More data for this Ligand-Target Pair
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of cGMP PDE II enzyme				J Med Chem 30: 1963-72 (1987) BindingDB Entry DOI: 10.7270/Q28K79P9
					More data for this Ligand-Target Pair
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of cyclic GMP sensitive phosphodiesterase PDE 2 of guinea pig ventricle				J Med Chem 28: 537-45 (1985) BindingDB Entry DOI: 10.7270/Q2N58MXT
					More data for this Ligand-Target Pair
Heart phosphodiesterase (Bos taurus)	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB MMDB KEGG B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ayerst Laboratories Research, Inc. Curated by ChEMBL					Assay Description Inhibition of bovine cardiac phosphodiesterase fraction III				J Med Chem 31: 814-23 (1988) BindingDB Entry DOI: 10.7270/Q2W096GV
					More data for this Ligand-Target Pair
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert/Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description Inhibition of Guinea Pig cAMP specific phosphodiesterase (PDE III); range 4 to 10				J Med Chem 30: 1724-8 (1987) BindingDB Entry DOI: 10.7270/Q20R9RN7
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration against cGMP PDE II enzyme in guinea pig				J Med Chem 30: 1955-62 (1987) BindingDB Entry DOI: 10.7270/Q27S7MS4
					More data for this Ligand-Target Pair
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration against cAMP PDE II enzyme in guinea pig				J Med Chem 30: 1955-62 (1987) BindingDB Entry DOI: 10.7270/Q27S7MS4
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration against cGMP PDE I enzyme in guinea pig				J Med Chem 30: 1955-62 (1987) BindingDB Entry DOI: 10.7270/Q27S7MS4
					More data for this Ligand-Target Pair
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration against cAMP PDE III enzyme in guinea pig				J Med Chem 30: 1955-62 (1987) BindingDB Entry DOI: 10.7270/Q27S7MS4
					More data for this Ligand-Target Pair
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of cGMP PDE II enzyme				J Med Chem 30: 1963-72 (1987) BindingDB Entry DOI: 10.7270/Q28K79P9
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of cAMP PDE I enzyme				J Med Chem 30: 1963-72 (1987) BindingDB Entry DOI: 10.7270/Q28K79P9
					More data for this Ligand-Target Pair
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of cGMP PDE II enzyme				J Med Chem 30: 1963-72 (1987) BindingDB Entry DOI: 10.7270/Q28K79P9
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition cGMP PDE I enzyme				J Med Chem 30: 1963-72 (1987) BindingDB Entry DOI: 10.7270/Q28K79P9
					More data for this Ligand-Target Pair
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Syntex Research Curated by ChEMBL					Assay Description Inhibition of human blood platelet c-AMP phosphodiesterase				J Med Chem 35: 620-8 (1992) BindingDB Entry DOI: 10.7270/Q2PZ57SK
					More data for this Ligand-Target Pair
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of PDE 3 (phosphodiesterase III) from guinea pig ventricle				J Med Chem 36: 1387-92 (1993) BindingDB Entry DOI: 10.7270/Q2JW8FHP
					More data for this Ligand-Target Pair
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of phosphodiesterase 3 from human platelets at 1E-7-1E-4M or 1.0E-6 to 1E-3 M				J Med Chem 32: 342-50 (1989) BindingDB Entry DOI: 10.7270/Q27083P1
					More data for this Ligand-Target Pair
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of low Km cyclic cAMP phosphodiesterase PDE III of guinea pig ventricle				J Med Chem 28: 537-45 (1985) BindingDB Entry DOI: 10.7270/Q2N58MXT
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of guinea pig ventricle				J Med Chem 28: 537-45 (1985) BindingDB Entry DOI: 10.7270/Q2N58MXT
					More data for this Ligand-Target Pair
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of guinea pig phosphodiesterase type III				J Med Chem 29: 261-7 (1986) BindingDB Entry DOI: 10.7270/Q2B56MZQ
					More data for this Ligand-Target Pair
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of canine cardiac cAMP phosphodiesterase (cAMP-PDE)				J Med Chem 30: 1342-7 (1987) BindingDB Entry DOI: 10.7270/Q2DV1N40
					More data for this Ligand-Target Pair
Phosphodiesterase 1 (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.40E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of fraction I of guinea pig phosphodiesterase				J Med Chem 27: 1099-101 (1984) BindingDB Entry DOI: 10.7270/Q26Q1W70
					More data for this Ligand-Target Pair
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM50000315 ((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...) Show SMILES O=C1CCC(=NN1)c1ccc(cc1)-n1ccnc1 |c:4| Show InChI InChI=1S/C13H12N4O/c18-13-6-5-12(15-16-13)10-1-3-11(4-2-10)17-8-7-14-9-17/h1-4,7-9H,5-6H2,(H,16,18)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration against cAMP PDE II enzyme in guinea pig				J Med Chem 30: 1955-62 (1987) BindingDB Entry DOI: 10.7270/Q27S7MS4
					More data for this Ligand-Target Pair