BDBM50000337 1-(2-Dimethylamino-ethyl)-4-(4-ethyl-phenyl)-3-methyl-6-trifluoromethyl-1,3,4,5-tetrahydro-benzo[b]azepin-2-one::CHEMBL165049

SMILES: CCc1ccc(cc1)[C@@H]1Cc2c(cccc2C(F)(F)F)N(CCN(C)C)C(=O)[C@@H]1C

InChI Key: InChIKey=MQZVQWKSGFGCNS-VQIMIIECSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000337   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated L-type calcium channel (Homo sapiens (Human))	BDBM50000337 (1-(2-Dimethylamino-ethyl)-4-(4-ethyl-phenyl)-3-met...) Show SMILES CCc1ccc(cc1)[C@@H]1Cc2c(cccc2C(F)(F)F)N(CCN(C)C)C(=O)[C@@H]1C Show InChI InChI=1S/C24H29F3N2O/c1-5-17-9-11-18(12-10-17)19-15-20-21(24(25,26)27)7-6-8-22(20)29(14-13-28(3)4)23(30)16(19)2/h6-12,16,19H,5,13-15H2,1-4H3/t16-,19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro ability to displace the specific binding of [3H]-diltiazem to diltiazem receptor in guinea pig skeletal muscle.				J Med Chem 35: 780-93 (1992) BindingDB Entry DOI: 10.7270/Q2K64H14
					More data for this Ligand-Target Pair