BDBM50000353 3-Allyl-1-(2-dimethylamino-ethyl)-4-(4-methoxy-phenyl)-1,3,4,5-tetrahydro-benzo[b]azepin-2-one::CHEMBL163740

SMILES: COc1ccc(cc1)[C@@H]1Cc2ccccc2N(CCN(C)C)C(=O)[C@@H]1CC=C

InChI Key: InChIKey=ZKDCTJVGBODVRR-YADHBBJMSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000353   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated L-type calcium channel (Homo sapiens (Human))	BDBM50000353 (3-Allyl-1-(2-dimethylamino-ethyl)-4-(4-methoxy-phe...) Show SMILES COc1ccc(cc1)[C@@H]1Cc2ccccc2N(CCN(C)C)C(=O)[C@@H]1CC=C Show InChI InChI=1S/C24H30N2O2/c1-5-8-21-22(18-11-13-20(28-4)14-12-18)17-19-9-6-7-10-23(19)26(24(21)27)16-15-25(2)3/h5-7,9-14,21-22H,1,8,15-17H2,2-4H3/t21-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro ability to displace the specific binding of [3H]-diltiazem to diltiazem receptor in guinea pig skeletal muscle.				J Med Chem 35: 780-93 (1992) BindingDB Entry DOI: 10.7270/Q2K64H14
					More data for this Ligand-Target Pair