BDBM50000362 Acetic acid 1-(2-dimethylamino-ethyl)-4-(4-methoxy-phenyl)-7-methylcarbamoyloxy-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl ester::CHEMBL349140

SMILES: CNC(=O)Oc1ccc2N(CCN(C)C)C(=O)[C@H](OC(C)=O)[C@@H](Cc2c1)c1ccc(OC)cc1

InChI Key: InChIKey=WNFIAHVGLPYZKH-JTHBVZDNSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000362   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated L-type calcium channel (Homo sapiens (Human))	BDBM50000362 (Acetic acid 1-(2-dimethylamino-ethyl)-4-(4-methoxy...) Show SMILES CNC(=O)Oc1ccc2N(CCN(C)C)C(=O)[C@H](OC(C)=O)[C@@H](Cc2c1)c1ccc(OC)cc1 Show InChI InChI=1S/C25H31N3O6/c1-16(29)33-23-21(17-6-8-19(32-5)9-7-17)15-18-14-20(34-25(31)26-2)10-11-22(18)28(24(23)30)13-12-27(3)4/h6-11,14,21,23H,12-13,15H2,1-5H3,(H,26,31)/t21-,23+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description In vitro ability to displace the specific binding of [3H]-diltiazem to diltiazem receptor in guinea pig skeletal muscle.				J Med Chem 35: 780-93 (1992) BindingDB Entry DOI: 10.7270/Q2K64H14
					More data for this Ligand-Target Pair