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BDBM50000465 CHEMBL555402

SMILES: Cl.O=C(N[C@@H]1CN2CCC1CC2)c1cccc2CCCCc12

InChI Key: InChIKey=MLYVCXQSTXUDJU-UNTBIKODSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50000465   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)		BDBM50000465
PNG
(CHEMBL555402)
Show SMILES Cl.O=C(N[C@@H]1CN2CCC1CC2)c1cccc2CCCCc12 |r,wU:4.2,(5.24,3.54,;-.26,3.7,;-1.33,3.08,;-2.66,3.86,;-2.65,5.41,;-1.23,6.18,;-1.22,7.79,;-2.74,7.54,;-2.78,6.29,;-4.07,6.2,;-4.04,7.82,;-2.61,8.62,;-1.33,1.54,;-2.69,.77,;-2.69,-.77,;-1.33,-1.54,;,-.77,;1.33,-1.54,;2.67,-.77,;2.67,.77,;1.33,1.54,;,.77,)|
Show InChI InChI=1S/C18H24N2O.ClH/c21-18(19-17-12-20-10-8-14(17)9-11-20)16-7-3-5-13-4-1-2-6-15(13)16;/h3,5,7,14,17H,1-2,4,6,8-12H2,(H,19,21);1H/t17-;/m1./s1
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PubMed
 200n/an/an/an/an/an/an/an/a



Syntex Research

Curated by ChEMBL


Assay Description
Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor in rat brain cortical membranes using radioligand [3H]quipazine

J Med Chem 36: 2645-57 (1993)

Checked by Author
BindingDB Entry DOI: 10.7270/Q2GM88T8
More data for this
Ligand-Target Pair